Intake of Lactobacillus reuteri improves incretin and insulin secretion in glucose-tolerant humans: a proof of concept

Ingestion of probiotics can modify gut microbiota and alter insulin resistance and diabetes development in rodents. We hypothesized that daily intake of Lactobacillus reuteri increases insulin sensitivity by changing cytokine release and insulin secretion via modulation of the release of glucagon-li...

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Veröffentlicht in:	Diabetes care 2015-10, Vol.38 (10), p.1827-1834
Hauptverfasser:	Simon, Marie-Christine, Strassburger, Klaus, Nowotny, Bettina, Kolb, Hubert, Nowotny, Peter, Burkart, Volker, Zivehe, Fariba, Hwang, Jong-Hee, Stehle, Peter, Pacini, Giovanni, Hartmann, Bolette, Holst, Jens J, MacKenzie, Colin, Bindels, Laure B, Martinez, Ines, Walter, Jens, Henrich, Birgit, Schloot, Nanette C, Roden, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Blood Glucose - metabolism C-Peptide - metabolism Cytokines Diabetes Diabetes Mellitus, Type 2 - metabolism Double-Blind Method Female Glucagon - metabolism Glucagon-Like Peptide 1 - metabolism Glucagon-Like Peptide 2 - metabolism Glucose Glucose - administration & dosage Glucose Clamp Technique Glucose Tolerance Test Humans Incretins - metabolism Insulin Insulin - metabolism Insulin Resistance - physiology Insulin Secretion Insulin-Secreting Cells - physiology Lactobacillus reuteri Male Middle Aged Obesity - metabolism Oxidative Stress - physiology Peptides Pilot Projects Probiotics Probiotics - pharmacology Prospective Studies Protein Precursors Rodents
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