The cardioprotective effect of salidroside against myocardial ischemia reperfusion injury in rats by inhibiting apoptosis and inflammation

The main purpose of this study was to investigate effect of salidroside (Sal) on myocardial ischemia reperfusion injury in rats and the underlying mechanism. Myocardial ischemia reperfusion injury (MI/RI) model was treated with 30 min of left anterior descending (LAD) occlusion followed by 24 h of r...

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Veröffentlicht in:	Apoptosis (London) 2015-11, Vol.20 (11), p.1433-1443
Hauptverfasser:	Zhu, Lingpeng, Wei, Tingting, Gao, Jin, Chang, Xiayun, He, He, Luo, Fen, Zhou, Rui, Ma, Chunhua, Liu, Yu, Yan, Tianhua
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects bcl-2-Associated X Protein - genetics bcl-2-Associated X Protein - immunology Biochemistry Biomedical and Life Sciences Biomedicine Cancer Research Caspase 3 - genetics Caspase 3 - immunology Caspase 9 - genetics Caspase 9 - immunology Cell Biology Glucosides - administration & dosage Humans Interleukin-1beta - genetics Interleukin-1beta - immunology Interleukin-6 - genetics Interleukin-6 - immunology Male Myocardial Reperfusion Injury - drug therapy Myocardial Reperfusion Injury - genetics Myocardial Reperfusion Injury - immunology Myocardial Reperfusion Injury - physiopathology Oncology Original Paper Phenols - administration & dosage Protective Agents - administration & dosage Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - immunology Rats Rats, Sprague-Dawley Toll-Like Receptor 4 - genetics Toll-Like Receptor 4 - immunology Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - immunology Virology
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