Evaluation of sex difference in tissue repair following acute carbon tetrachloride toxicity in male and female Sprague–Dawley rats

Cellular regeneration and tissue repair greatly influence the outcome of acute carbon tetrachloride (CCl 4) hepatotoxicity. This study examined the temporal kinetics of cellular regeneration and tissue repair processes in male and female Sprague–Dawley (SD) rats following an acute CCl 4 exposure (0....

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Veröffentlicht in:	Toxicology (Amsterdam) 1998-09, Vol.130 (2), p.95-105
Hauptverfasser:	Moghaddam, Abdollah P., Eggers, Jeffrey S., Calabrese, Edward J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - blood Animals Aspartate Aminotransferases - blood Biological and medical sciences Blood Glucose Carbon Tetrachloride - toxicity CCl4 Cell Count Cell Cycle - drug effects Chemical and industrial products toxicology. Toxic occupational diseases Cytochrome P-450 CYP2E1 - metabolism Female L-Lactate Dehydrogenase - blood Liver Liver - drug effects Liver - enzymology Liver - physiopathology Liver Regeneration - physiology Male Medical sciences Necrosis Nutrition Proliferating Cell Nuclear Antigen - metabolism Rats Rats, Sprague-Dawley Repair Sex Sex Characteristics Solvents Time Factors Toxicology Triglycerides - blood
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