Properties of ectopic neurons induced by Xenopus neurogenin1 misexpression

We have examined cells cultured from ectoderm-misexpressing Neurogenin1 (Ngn1) to describe better the extent to which this gene can control aspects of neuronal phenotype including motility, morphology, excitability, and synaptic properties. Like primary spinal neurons which normally express Ngn1, ce...

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Veröffentlicht in:	Molecular and cellular neuroscience 1998-11, Vol.12 (4-5), p.281-299
Hauptverfasser:	Olson, E C, Schinder, A F, Dantzker, J L, Marcus, E A, Spitzer, N C, Harris, W A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Calcium-Calmodulin-Dependent Protein Kinases - metabolism Cell Differentiation Cell Movement Cells, Cultured Choristoma - genetics Ectoderm - cytology Ectoderm - physiology Embryo, Nonmammalian - physiology Female Freshwater Glycogen Synthase Kinase 3 Helix-Loop-Helix Motifs Male Mutation, Missense Nerve Tissue Proteins - genetics Nervous System Diseases - embryology Nervous System Diseases - genetics Neurons - drug effects Neurons - pathology Neurons - physiology Synapses - physiology Tetrodotoxin - pharmacology Transcription Factors Xenopus
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