A Gene Upregulated in the Acoustically Damaged Chick Basilar Papilla Encodes a Novel WD40 Repeat Protein

The chickWDR1gene is expressed at higher levels in the chick basilar papilla after acoustic overstimulation. The 3.3-kbWDR1cDNA encodes a novel 67-kDa protein containing nine WD40 repeats, motifs that mediate protein–protein interactions. The predicted WDR1 protein has high sequence identity to WD40...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 1999-02, Vol.56 (1), p.59-69
Hauptverfasser:	Adler, Henry J., Winnicki, Robert S., Gong, Tzy-Wen L., Lomax, Margaret I.
Format:	Artikel
Sprache:	eng
Schlagworte:	actin actin binding proteins Actins - genetics Amino Acid Sequence amino acid sequences Animals Base Sequence Basilar Membrane - metabolism binding proteins Biological and medical sciences Caenorhabditis elegans chickens Chickens - genetics Chickens - physiology chromosome mapping Chromosomes, Human, Pair 4 - genetics complementary DNA Dictyostelium discoideum ears Fundamental and applied biological sciences. Psychology genbank/af020054 genbank/af020055 genbank/af020056 genbank/af020260 Gene Expression gene location Genes. Genome genetic regulation Hearing Loss, Noise-Induced - genetics Humans messenger RNA Mice Microfilament Proteins - genetics Molecular and cellular biology Molecular genetics Molecular Sequence Data noise trauma Nucleic Acid Hybridization nucleotide sequences Physarum polycephalum Restriction Mapping Saccharomyces cerevisiae Sequence Alignment Sequence Homology, Amino Acid sounds species differences structural genes wdr1 gene
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