E-selectin Gene Expression Is Induced Synergistically with the Coexistence of Activated Classic Protein Kinase C and Signals Elicited by Interleukin-1β but Not Tumor Necrosis Factor-α

We have examined the effect of protein kinase C (PKC) on the expression of the E-selectin and intercellular adhesion molecule-1 (ICAM-1) mRNAs in human umbilical vein endothelial cells. The lower classic PKC activity on pretreatment with phorbol ester (phorbol 12-myristate 13-acetate (PMA)) for 24 h...

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Veröffentlicht in:	The Journal of biological chemistry 1999-02, Vol.274 (6), p.3753-3763
Hauptverfasser:	Tamaru, Masahiro, Narumi, Shosaku
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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