Lateral pharyngeal wall collapse associated with hypoxemia in obstructive sleep apnea
Objectives/Hypothesis Review drug‐induced sleep endoscopy (DISE) findings and correlate the patterns of airway collapse with body mass index (BMI) and objective sleep study respiratory variables, with particular emphasis on oxygen desaturation variables. Study Design Retrospective chart review. Meth...
Gespeichert in:
| Veröffentlicht in: | The Laryngoscope 2015-10, Vol.125 (10), p.2408-2412 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2412 |
|---|---|
| container_issue | 10 |
| container_start_page | 2408 |
| container_title | The Laryngoscope |
| container_volume | 125 |
| creator | Lan, Ming-Chin Liu, Stanley Y. C. Lan, Ming-Ying Modi, Rahul Capasso, Robson |
| description | Objectives/Hypothesis
Review drug‐induced sleep endoscopy (DISE) findings and correlate the patterns of airway collapse with body mass index (BMI) and objective sleep study respiratory variables, with particular emphasis on oxygen desaturation variables.
Study Design
Retrospective chart review.
Methods
From January 2010 to March 2014, 64 patients underwent DISE, and its findings were registered using the VOTE (velum, oropharynx, tongue base, epiglottis) classification system. Associations were analyzed between DISE, BMI, and polysomnographic parameters.
Results
Complete lateral oropharyngeal collapse was significantly associated with increased severity of obstructive sleep apnea (OSA), reflected by a higher oxygen desaturation index, apnea‐hypopnea index, apnea index, the percent of the total time with oxygen saturation level lower than 90%, and minimal oxygen saturation). Complete concentric collapse of the velum and complete lateral oropharyngeal collapse were associated with higher BMI values.
Conclusions
The results of this study demonstrate a strong association between complete lateral oropharyngeal wall collapse and increased OSA severity, particularly with objective oximetry measures. Patients with a complete lateral oropharyngeal wall collapse may need aggressive treatment strategies because of the high probability of subsequent cardiovascular complications.
Level of Evidence
4 Laryngoscope, 125:2408–2412, 2015 |
| doi_str_mv | 10.1002/lary.25126 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1715917194</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1715917194</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4656-c0dc9f54d878b4e0226e0c526b013dbc98260e20c3794b27842f26a7ea843ca53</originalsourceid><addsrcrecordid>eNp9kE1LHDEYgIO06FZ78QeUgBcpjOZzJjmKVFsYrIjS9hQymXfd2OzMNJlx3X_fbFc9eOglCeR5H14ehA4pOaGEsNNg4_qEScrKHTSjktNCaC3foVn-5IWS7Oce-pDSAyG04pLsoj0mpWJCqxm6q-0I0QY8LLKlu4f8XNkQsOtDsEMCbFPqnc9Ui1d-XODFeuifYOkt9h3umzTGyY3-EXAKAAO2Qwf2AL2f25Dg4_O9j-4uvtyefy3q75ffzs_qwolSloUjrdNzKVpVqUYAYawE4iQrG0J52zitWEmAEccrLRpWKcHmrLQVWCW4s5Lvo-Otd4j9nwnSaJY-Ocibd9BPydCKSp0PLTJ69AZ96KfY5e02FNecC6Uy9XlLudinFGFuhuiXuYyhxGxim01s8y92hj89K6dmCe0r-lI3A3QLrHyA9X9Upj67-fUiLbYzPo3w9Dpj429TVryS5sfVpRGCXtxe1deG8L9is5ir</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1713933488</pqid></control><display><type>article</type><title>Lateral pharyngeal wall collapse associated with hypoxemia in obstructive sleep apnea</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Lan, Ming-Chin ; Liu, Stanley Y. C. ; Lan, Ming-Ying ; Modi, Rahul ; Capasso, Robson</creator><creatorcontrib>Lan, Ming-Chin ; Liu, Stanley Y. C. ; Lan, Ming-Ying ; Modi, Rahul ; Capasso, Robson</creatorcontrib><description>Objectives/Hypothesis
Review drug‐induced sleep endoscopy (DISE) findings and correlate the patterns of airway collapse with body mass index (BMI) and objective sleep study respiratory variables, with particular emphasis on oxygen desaturation variables.
Study Design
Retrospective chart review.
Methods
From January 2010 to March 2014, 64 patients underwent DISE, and its findings were registered using the VOTE (velum, oropharynx, tongue base, epiglottis) classification system. Associations were analyzed between DISE, BMI, and polysomnographic parameters.
Results
Complete lateral oropharyngeal collapse was significantly associated with increased severity of obstructive sleep apnea (OSA), reflected by a higher oxygen desaturation index, apnea‐hypopnea index, apnea index, the percent of the total time with oxygen saturation level lower than 90%, and minimal oxygen saturation). Complete concentric collapse of the velum and complete lateral oropharyngeal collapse were associated with higher BMI values.
Conclusions
The results of this study demonstrate a strong association between complete lateral oropharyngeal wall collapse and increased OSA severity, particularly with objective oximetry measures. Patients with a complete lateral oropharyngeal wall collapse may need aggressive treatment strategies because of the high probability of subsequent cardiovascular complications.
Level of Evidence
4 Laryngoscope, 125:2408–2412, 2015</description><identifier>ISSN: 0023-852X</identifier><identifier>EISSN: 1531-4995</identifier><identifier>DOI: 10.1002/lary.25126</identifier><identifier>PMID: 25582498</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Adult ; apnea-hypopnea index ; Body Mass Index ; Drug-induced sleep endoscopy ; Female ; Humans ; Hypoxia - pathology ; Hypoxia - physiopathology ; Male ; Middle Aged ; oxygen desaturation index ; Pharynx - pathology ; Pharynx - physiopathology ; Polysomnography ; Retrospective Studies ; Sleep apnea ; Sleep Apnea, Obstructive - pathology ; Sleep Apnea, Obstructive - physiopathology ; Sleep disorders</subject><ispartof>The Laryngoscope, 2015-10, Vol.125 (10), p.2408-2412</ispartof><rights>2015 The American Laryngological, Rhinological and Otological Society, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4656-c0dc9f54d878b4e0226e0c526b013dbc98260e20c3794b27842f26a7ea843ca53</citedby><cites>FETCH-LOGICAL-c4656-c0dc9f54d878b4e0226e0c526b013dbc98260e20c3794b27842f26a7ea843ca53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Flary.25126$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Flary.25126$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25582498$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lan, Ming-Chin</creatorcontrib><creatorcontrib>Liu, Stanley Y. C.</creatorcontrib><creatorcontrib>Lan, Ming-Ying</creatorcontrib><creatorcontrib>Modi, Rahul</creatorcontrib><creatorcontrib>Capasso, Robson</creatorcontrib><title>Lateral pharyngeal wall collapse associated with hypoxemia in obstructive sleep apnea</title><title>The Laryngoscope</title><addtitle>The Laryngoscope</addtitle><description>Objectives/Hypothesis
Review drug‐induced sleep endoscopy (DISE) findings and correlate the patterns of airway collapse with body mass index (BMI) and objective sleep study respiratory variables, with particular emphasis on oxygen desaturation variables.
Study Design
Retrospective chart review.
Methods
From January 2010 to March 2014, 64 patients underwent DISE, and its findings were registered using the VOTE (velum, oropharynx, tongue base, epiglottis) classification system. Associations were analyzed between DISE, BMI, and polysomnographic parameters.
Results
Complete lateral oropharyngeal collapse was significantly associated with increased severity of obstructive sleep apnea (OSA), reflected by a higher oxygen desaturation index, apnea‐hypopnea index, apnea index, the percent of the total time with oxygen saturation level lower than 90%, and minimal oxygen saturation). Complete concentric collapse of the velum and complete lateral oropharyngeal collapse were associated with higher BMI values.
Conclusions
The results of this study demonstrate a strong association between complete lateral oropharyngeal wall collapse and increased OSA severity, particularly with objective oximetry measures. Patients with a complete lateral oropharyngeal wall collapse may need aggressive treatment strategies because of the high probability of subsequent cardiovascular complications.
Level of Evidence
4 Laryngoscope, 125:2408–2412, 2015</description><subject>Adult</subject><subject>apnea-hypopnea index</subject><subject>Body Mass Index</subject><subject>Drug-induced sleep endoscopy</subject><subject>Female</subject><subject>Humans</subject><subject>Hypoxia - pathology</subject><subject>Hypoxia - physiopathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>oxygen desaturation index</subject><subject>Pharynx - pathology</subject><subject>Pharynx - physiopathology</subject><subject>Polysomnography</subject><subject>Retrospective Studies</subject><subject>Sleep apnea</subject><subject>Sleep Apnea, Obstructive - pathology</subject><subject>Sleep Apnea, Obstructive - physiopathology</subject><subject>Sleep disorders</subject><issn>0023-852X</issn><issn>1531-4995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LHDEYgIO06FZ78QeUgBcpjOZzJjmKVFsYrIjS9hQymXfd2OzMNJlx3X_fbFc9eOglCeR5H14ehA4pOaGEsNNg4_qEScrKHTSjktNCaC3foVn-5IWS7Oce-pDSAyG04pLsoj0mpWJCqxm6q-0I0QY8LLKlu4f8XNkQsOtDsEMCbFPqnc9Ui1d-XODFeuifYOkt9h3umzTGyY3-EXAKAAO2Qwf2AL2f25Dg4_O9j-4uvtyefy3q75ffzs_qwolSloUjrdNzKVpVqUYAYawE4iQrG0J52zitWEmAEccrLRpWKcHmrLQVWCW4s5Lvo-Otd4j9nwnSaJY-Ocibd9BPydCKSp0PLTJ69AZ96KfY5e02FNecC6Uy9XlLudinFGFuhuiXuYyhxGxim01s8y92hj89K6dmCe0r-lI3A3QLrHyA9X9Upj67-fUiLbYzPo3w9Dpj429TVryS5sfVpRGCXtxe1deG8L9is5ir</recordid><startdate>201510</startdate><enddate>201510</enddate><creator>Lan, Ming-Chin</creator><creator>Liu, Stanley Y. C.</creator><creator>Lan, Ming-Ying</creator><creator>Modi, Rahul</creator><creator>Capasso, Robson</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201510</creationdate><title>Lateral pharyngeal wall collapse associated with hypoxemia in obstructive sleep apnea</title><author>Lan, Ming-Chin ; Liu, Stanley Y. C. ; Lan, Ming-Ying ; Modi, Rahul ; Capasso, Robson</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4656-c0dc9f54d878b4e0226e0c526b013dbc98260e20c3794b27842f26a7ea843ca53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>apnea-hypopnea index</topic><topic>Body Mass Index</topic><topic>Drug-induced sleep endoscopy</topic><topic>Female</topic><topic>Humans</topic><topic>Hypoxia - pathology</topic><topic>Hypoxia - physiopathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>oxygen desaturation index</topic><topic>Pharynx - pathology</topic><topic>Pharynx - physiopathology</topic><topic>Polysomnography</topic><topic>Retrospective Studies</topic><topic>Sleep apnea</topic><topic>Sleep Apnea, Obstructive - pathology</topic><topic>Sleep Apnea, Obstructive - physiopathology</topic><topic>Sleep disorders</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lan, Ming-Chin</creatorcontrib><creatorcontrib>Liu, Stanley Y. C.</creatorcontrib><creatorcontrib>Lan, Ming-Ying</creatorcontrib><creatorcontrib>Modi, Rahul</creatorcontrib><creatorcontrib>Capasso, Robson</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>The Laryngoscope</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lan, Ming-Chin</au><au>Liu, Stanley Y. C.</au><au>Lan, Ming-Ying</au><au>Modi, Rahul</au><au>Capasso, Robson</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lateral pharyngeal wall collapse associated with hypoxemia in obstructive sleep apnea</atitle><jtitle>The Laryngoscope</jtitle><addtitle>The Laryngoscope</addtitle><date>2015-10</date><risdate>2015</risdate><volume>125</volume><issue>10</issue><spage>2408</spage><epage>2412</epage><pages>2408-2412</pages><issn>0023-852X</issn><eissn>1531-4995</eissn><abstract>Objectives/Hypothesis
Review drug‐induced sleep endoscopy (DISE) findings and correlate the patterns of airway collapse with body mass index (BMI) and objective sleep study respiratory variables, with particular emphasis on oxygen desaturation variables.
Study Design
Retrospective chart review.
Methods
From January 2010 to March 2014, 64 patients underwent DISE, and its findings were registered using the VOTE (velum, oropharynx, tongue base, epiglottis) classification system. Associations were analyzed between DISE, BMI, and polysomnographic parameters.
Results
Complete lateral oropharyngeal collapse was significantly associated with increased severity of obstructive sleep apnea (OSA), reflected by a higher oxygen desaturation index, apnea‐hypopnea index, apnea index, the percent of the total time with oxygen saturation level lower than 90%, and minimal oxygen saturation). Complete concentric collapse of the velum and complete lateral oropharyngeal collapse were associated with higher BMI values.
Conclusions
The results of this study demonstrate a strong association between complete lateral oropharyngeal wall collapse and increased OSA severity, particularly with objective oximetry measures. Patients with a complete lateral oropharyngeal wall collapse may need aggressive treatment strategies because of the high probability of subsequent cardiovascular complications.
Level of Evidence
4 Laryngoscope, 125:2408–2412, 2015</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>25582498</pmid><doi>10.1002/lary.25126</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0023-852X |
| ispartof | The Laryngoscope, 2015-10, Vol.125 (10), p.2408-2412 |
| issn | 0023-852X 1531-4995 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1715917194 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult apnea-hypopnea index Body Mass Index Drug-induced sleep endoscopy Female Humans Hypoxia - pathology Hypoxia - physiopathology Male Middle Aged oxygen desaturation index Pharynx - pathology Pharynx - physiopathology Polysomnography Retrospective Studies Sleep apnea Sleep Apnea, Obstructive - pathology Sleep Apnea, Obstructive - physiopathology Sleep disorders |
| title | Lateral pharyngeal wall collapse associated with hypoxemia in obstructive sleep apnea |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T00%3A55%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lateral%20pharyngeal%20wall%20collapse%20associated%20with%20hypoxemia%20in%20obstructive%20sleep%20apnea&rft.jtitle=The%20Laryngoscope&rft.au=Lan,%20Ming-Chin&rft.date=2015-10&rft.volume=125&rft.issue=10&rft.spage=2408&rft.epage=2412&rft.pages=2408-2412&rft.issn=0023-852X&rft.eissn=1531-4995&rft_id=info:doi/10.1002/lary.25126&rft_dat=%3Cproquest_cross%3E1715917194%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1713933488&rft_id=info:pmid/25582498&rfr_iscdi=true |