Postoperative Deep Infection After Cemented Versus Cementless Total Hip Arthroplasty: A Meta-Analysis
Abstract Periprosthetic joint infection (PJI) is a serious complication of total hip arthroplasty (THA). The objective of this meta-analysis was to compare the PJI rate between cemented and cementless THAs. Eight clinical studies (2 randomized controlled trials and 6 observational studies) were avai...
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| Veröffentlicht in: | The Journal of arthroplasty 2015-10, Vol.30 (10), p.1823-1827 |
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| creator | Yoon, Byung-Ho, MD Ha, Yong-Chan, MD Lee, Young-Kyun, MD Koo, Kyung-Hoi, MD |
| description | Abstract Periprosthetic joint infection (PJI) is a serious complication of total hip arthroplasty (THA). The objective of this meta-analysis was to compare the PJI rate between cemented and cementless THAs. Eight clinical studies (2 randomized controlled trials and 6 observational studies) were available for the analysis. Meta-analysis (with a fixed-effects model) and subgroup analysis were performed by research design and meta-regression was performed by continuous moderator. The overall incidence of PJI was 0.4% (357/84,200). The incidence was 0.5% (310/67,531) in cemented group, and 0.3% (47/16,669) in cementless group ( P = 0.008). The meta-analysis revealed that the use of cement in THA was associated with an increased risk of PJI (odds ratio 1.53; 95% confidence interval 1.120 to 2.100; P = 0.008). |
| doi_str_mv | 10.1016/j.arth.2015.04.041 |
| format | Article |
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The objective of this meta-analysis was to compare the PJI rate between cemented and cementless THAs. Eight clinical studies (2 randomized controlled trials and 6 observational studies) were available for the analysis. Meta-analysis (with a fixed-effects model) and subgroup analysis were performed by research design and meta-regression was performed by continuous moderator. The overall incidence of PJI was 0.4% (357/84,200). The incidence was 0.5% (310/67,531) in cemented group, and 0.3% (47/16,669) in cementless group ( P = 0.008). The meta-analysis revealed that the use of cement in THA was associated with an increased risk of PJI (odds ratio 1.53; 95% confidence interval 1.120 to 2.100; P = 0.008).</description><identifier>ISSN: 0883-5403</identifier><identifier>EISSN: 1532-8406</identifier><identifier>DOI: 10.1016/j.arth.2015.04.041</identifier><identifier>PMID: 26021907</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Arthritis, Infectious ; Arthroplasty, Replacement, Hip - adverse effects ; Bone Cements - therapeutic use ; cemented ; cementless ; Hip Prosthesis - adverse effects ; Humans ; Incidence ; infection ; meta-analysis ; Observational Studies as Topic ; Odds Ratio ; Orthopedics ; Postoperative Complications - etiology ; Prosthesis-Related Infections - diagnosis ; Prosthesis-Related Infections - epidemiology ; Randomized Controlled Trials as Topic ; Regression Analysis ; total hip arthroplasty</subject><ispartof>The Journal of arthroplasty, 2015-10, Vol.30 (10), p.1823-1827</ispartof><rights>Elsevier Inc.</rights><rights>2015 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-41ccf2f5e8da5980c8444406a9ed9bdb9eb854e2c121f94df9971cf7f825d6033</citedby><cites>FETCH-LOGICAL-c481t-41ccf2f5e8da5980c8444406a9ed9bdb9eb854e2c121f94df9971cf7f825d6033</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.arth.2015.04.041$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26021907$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yoon, Byung-Ho, MD</creatorcontrib><creatorcontrib>Ha, Yong-Chan, MD</creatorcontrib><creatorcontrib>Lee, Young-Kyun, MD</creatorcontrib><creatorcontrib>Koo, Kyung-Hoi, MD</creatorcontrib><title>Postoperative Deep Infection After Cemented Versus Cementless Total Hip Arthroplasty: A Meta-Analysis</title><title>The Journal of arthroplasty</title><addtitle>J Arthroplasty</addtitle><description>Abstract Periprosthetic joint infection (PJI) is a serious complication of total hip arthroplasty (THA). The objective of this meta-analysis was to compare the PJI rate between cemented and cementless THAs. Eight clinical studies (2 randomized controlled trials and 6 observational studies) were available for the analysis. Meta-analysis (with a fixed-effects model) and subgroup analysis were performed by research design and meta-regression was performed by continuous moderator. The overall incidence of PJI was 0.4% (357/84,200). The incidence was 0.5% (310/67,531) in cemented group, and 0.3% (47/16,669) in cementless group ( P = 0.008). The meta-analysis revealed that the use of cement in THA was associated with an increased risk of PJI (odds ratio 1.53; 95% confidence interval 1.120 to 2.100; P = 0.008).</description><subject>Arthritis, Infectious</subject><subject>Arthroplasty, Replacement, Hip - adverse effects</subject><subject>Bone Cements - therapeutic use</subject><subject>cemented</subject><subject>cementless</subject><subject>Hip Prosthesis - adverse effects</subject><subject>Humans</subject><subject>Incidence</subject><subject>infection</subject><subject>meta-analysis</subject><subject>Observational Studies as Topic</subject><subject>Odds Ratio</subject><subject>Orthopedics</subject><subject>Postoperative Complications - etiology</subject><subject>Prosthesis-Related Infections - diagnosis</subject><subject>Prosthesis-Related Infections - epidemiology</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Regression Analysis</subject><subject>total hip arthroplasty</subject><issn>0883-5403</issn><issn>1532-8406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kVGL1DAUhYMo7uzqH_BB8uhLx9w06TQiQhldd2FFwdXXkElvMGOnqUm6MP_elBl98MFwIQTOOeR8l5AXwNbAoHm9X5uYf6w5A7lmogw8IiuQNa9awZrHZMXatq6kYPUFuUxpzxiAlOIpueAN46DYZkXwS0g5TBhN9g9I3yNO9HZ0aLMPI-1cxki3eMAxY0-_Y0xzOr8HTIneh2wGeuMn2pWvxDANJuXjG9rRT5hN1Y1mOCafnpEnzgwJn5_vK_Lt-sP99qa6-_zxdtvdVVa0kCsB1jruJLa9kaplthXlsMYo7NWu3ynctVIgt8DBKdE7pTZg3ca1XPYNq-sr8uqUO8Xwa8aU9cEni8NgRgxz0rAB2Uil1CLlJ6mNIaWITk_RH0w8amB6wav3esGrF7yaiTJQTC_P-fPugP1fyx-eRfD2JMDS8sFj1Ml6HC32Phamug_-__nv_rHbwY_emuEnHjHtwxwL0dJDJ66Z_roseNkvSFbag6p_A9RIoQo</recordid><startdate>20151001</startdate><enddate>20151001</enddate><creator>Yoon, Byung-Ho, MD</creator><creator>Ha, Yong-Chan, MD</creator><creator>Lee, Young-Kyun, MD</creator><creator>Koo, Kyung-Hoi, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20151001</creationdate><title>Postoperative Deep Infection After Cemented Versus Cementless Total Hip Arthroplasty: A Meta-Analysis</title><author>Yoon, Byung-Ho, MD ; Ha, Yong-Chan, MD ; Lee, Young-Kyun, MD ; Koo, Kyung-Hoi, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-41ccf2f5e8da5980c8444406a9ed9bdb9eb854e2c121f94df9971cf7f825d6033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Arthritis, Infectious</topic><topic>Arthroplasty, Replacement, Hip - adverse effects</topic><topic>Bone Cements - therapeutic use</topic><topic>cemented</topic><topic>cementless</topic><topic>Hip Prosthesis - adverse effects</topic><topic>Humans</topic><topic>Incidence</topic><topic>infection</topic><topic>meta-analysis</topic><topic>Observational Studies as Topic</topic><topic>Odds Ratio</topic><topic>Orthopedics</topic><topic>Postoperative Complications - etiology</topic><topic>Prosthesis-Related Infections - diagnosis</topic><topic>Prosthesis-Related Infections - epidemiology</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Regression Analysis</topic><topic>total hip arthroplasty</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yoon, Byung-Ho, MD</creatorcontrib><creatorcontrib>Ha, Yong-Chan, MD</creatorcontrib><creatorcontrib>Lee, Young-Kyun, MD</creatorcontrib><creatorcontrib>Koo, Kyung-Hoi, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of arthroplasty</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yoon, Byung-Ho, MD</au><au>Ha, Yong-Chan, MD</au><au>Lee, Young-Kyun, MD</au><au>Koo, Kyung-Hoi, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Postoperative Deep Infection After Cemented Versus Cementless Total Hip Arthroplasty: A Meta-Analysis</atitle><jtitle>The Journal of arthroplasty</jtitle><addtitle>J Arthroplasty</addtitle><date>2015-10-01</date><risdate>2015</risdate><volume>30</volume><issue>10</issue><spage>1823</spage><epage>1827</epage><pages>1823-1827</pages><issn>0883-5403</issn><eissn>1532-8406</eissn><abstract>Abstract Periprosthetic joint infection (PJI) is a serious complication of total hip arthroplasty (THA). The objective of this meta-analysis was to compare the PJI rate between cemented and cementless THAs. Eight clinical studies (2 randomized controlled trials and 6 observational studies) were available for the analysis. Meta-analysis (with a fixed-effects model) and subgroup analysis were performed by research design and meta-regression was performed by continuous moderator. The overall incidence of PJI was 0.4% (357/84,200). The incidence was 0.5% (310/67,531) in cemented group, and 0.3% (47/16,669) in cementless group ( P = 0.008). The meta-analysis revealed that the use of cement in THA was associated with an increased risk of PJI (odds ratio 1.53; 95% confidence interval 1.120 to 2.100; P = 0.008).</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26021907</pmid><doi>10.1016/j.arth.2015.04.041</doi><tpages>5</tpages></addata></record> |
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| subjects | Arthritis, Infectious Arthroplasty, Replacement, Hip - adverse effects Bone Cements - therapeutic use cemented cementless Hip Prosthesis - adverse effects Humans Incidence infection meta-analysis Observational Studies as Topic Odds Ratio Orthopedics Postoperative Complications - etiology Prosthesis-Related Infections - diagnosis Prosthesis-Related Infections - epidemiology Randomized Controlled Trials as Topic Regression Analysis total hip arthroplasty |
| title | Postoperative Deep Infection After Cemented Versus Cementless Total Hip Arthroplasty: A Meta-Analysis |
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