The solution structure of a cytotoxic ribonuclease from the oocytes of Rana catesbeiana (bullfrog)

RC-RNase is a pyrimidine-guanine sequence-specific ribonuclease and a lectin possessing potent cell cytotoxicity. It was isolated from the oocytes of Rana catesbeiana (bull frog). From analysis of an extensive set of 1H homonuclear 2D NMR spectra we have completed the resonance assignments. Determin...

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Veröffentlicht in:	Journal of molecular biology 1998, Vol.283 (1), p.231-244
Hauptverfasser:	Chang, Chi-Fon, Chen, Chinpan, Chen, Yi-Cheng, Hom, Kellie, Huang, Rong-Fong, Huang, Tai-huang
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphibian Proteins Animals Binding Sites Crystallography, X-Ray cytotoxic protein Cytotoxins - antagonists & inhibitors Cytotoxins - chemistry Deoxycytosine Nucleotides - chemistry Deoxyguanosine - analogs & derivatives Deoxyguanosine - chemistry Dinucleoside Phosphates - chemistry Egg Proteins - chemistry Endoribonucleases - antagonists & inhibitors Endoribonucleases - chemistry Enzyme Inhibitors - chemistry Freshwater lectin Models, Molecular NMR Nuclear Magnetic Resonance, Biomolecular - methods Oocytes - enzymology Protein Structure, Secondary Protein Structure, Tertiary Rana catesbeiana RC-RNase sialic acid
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