The ATP‐binding cassette subunit of the maltose transporter MalK antagonizes MalT, the activator of the Escherichia coli mal regulon

Transcription of the mal regulon of Escherichia coli K‐12 is regulated by the positive activator, MalT. In the presence of ATP and maltotriose, MalT binds to decanucleotide MalT boxes that are found upstream of mal promoters and activates transcription at these sites. The earliest studies of the mal...

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Veröffentlicht in:	Molecular microbiology 1998-11, Vol.30 (3), p.535-546
Hauptverfasser:	Panagiotidis, Cynthia H., Boos, Winfried, Shuman, Howard A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - metabolism ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - metabolism Bacterial Proteins - genetics Bacterial Proteins - metabolism Biological Transport - genetics Carrier Proteins - genetics DNA-Binding Proteins - genetics Down-Regulation - genetics Escherichia coli Escherichia coli Proteins Gene Expression Regulation, Bacterial - genetics Genes, Bacterial - genetics Isopropyl Thiogalactoside - pharmacology Maltose-Binding Proteins Monosaccharide Transport Proteins Mutation - genetics Transcription Factors Transcriptional Activation - genetics Trisaccharides - metabolism
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