Induction of Peripheral Tolerance in Neonatally Thymectomized Mice by Immunization through Chemical Carcinogen-Altered Skin

BALB/c mice thymectomized 3 days after birth (3dnTx) are prone to the development of autoimmune gastritis. As this outcome may be a consequence of altered immunoregulatory mechanisms, we set out to determine the immunological status of these mice and their capacity to acquire antigen-specific periph...

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Veröffentlicht in:	Cellular immunology 1998-11, Vol.189 (2), p.99-106
Hauptverfasser:	Chen, Y.P., Muller, H.K., Scarff, K., Toh, B.H., Woods, G.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene - toxicity Animals Animals, Newborn - immunology Antibody Formation Autoimmune Diseases - etiology Gastritis - etiology Immune Tolerance Immunization Lymphocyte Activation Mice Mice, Inbred BALB C Picryl Chloride - immunology Skin - drug effects Thymectomy
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