Anti-cancer effects of enteric-coated polymers containing mistletoe lectin in murine melanoma cells in vitro and in vivo

In this study, we evaluated the effects of Korean mistletoe ( Viscum album L. var. coloratum ) coated with a biodegradable polymer (Eudragit ® ) wall on the growth of mouse melanoma in vivo. Oral administration of 4 % (430 mg/kg/day) enteric-coated mistletoe resulted in a significant reduction in tu...

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Veröffentlicht in:	Molecular and cellular biochemistry 2015-10, Vol.408 (1-2), p.73-87
Hauptverfasser:	Han, Seung-Yeon, Hong, Chang-Eui, Kim, Hwan-Gyu, Lyu, Su-Yun
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Analysis Animals Antineoplastic Agents, Phytogenic - administration & dosage Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - pharmacology Apoptosis Biochemistry Biodegradation Biomedical and Life Sciences Cancer Cardiology Care and treatment Caspase 3 - metabolism Caspase 8 - metabolism Cell Cycle - drug effects Cell growth Cell Line, Tumor Drug Screening Assays, Antitumor Gene Expression Regulation, Neoplastic - drug effects In Vitro Techniques Lectins Life Sciences Medical Biochemistry Melanoma Melanoma, Experimental - drug therapy Melanoma, Experimental - metabolism Mice Mistletoe - metabolism Oncology Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Lectins - administration & dosage Plant Lectins - chemistry Plant Lectins - pharmacology Polymers Polymers - chemistry Ribosome Inactivating Proteins - administration & dosage Ribosome Inactivating Proteins - chemistry Ribosome Inactivating Proteins - pharmacology Skin Neoplasms - drug therapy Skin Neoplasms - metabolism Survival Survival Analysis Tumors
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