Genomic and transcriptional alterations in mouse fetus liver after transplacental exposure to cigarette smoke

ABSTRACT The transplacental exposure of fetuses to maternal cigarette smoke may increase the risk of developmental impairments, congenital diseases, and childhood cancer. The whole‐body exposure of Swiss mice to environmental cigarette smoke (ECS) during pregnancy decreased the number of fetuses per...

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Veröffentlicht in:	The FASEB journal 2003-06, Vol.17 (9), p.1127-1129
Hauptverfasser:	Izzotti, Alberto, Balansky, Roumen M., Cartiglia, Cristina, Camoirano, Anna, Longobardi, Mariagrazia, De Flora, Silvio
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine - pharmacology Animals Anticarcinogenic Agents - pharmacology Apoptosis Cell Cycle - drug effects Cell Division - drug effects Cell Hypoxia DNA Adducts - metabolism DNA Repair Female Fetus - anatomy & histology Fetus - drug effects Gene Expression Regulation - drug effects Genome genomic alterations Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - drug effects Liver - drug effects Liver - embryology Liver - metabolism Maternal Exposure Mice mouse liver development multigene expression analysis N‐acetylcysteine Oxidation-Reduction Oxidative Stress Parity - drug effects Placenta - anatomy & histology Placenta - drug effects Pregnancy Smoking - adverse effects Transcription, Genetic transplacental cigarette smoke
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