Transmission of Integrated Human Herpesvirus 6 through Stem Cell Transplantation: Implications for Laboratory Diagnosis

We identified a stem cell donor with chromosomally integrated human herpesvirus (HHV)–6 and monitored the recipient for HHV-6 after transplantation. The appearance and subsequent increase in HHV-6 load paralleled engraftment and an increase in white blood cell count. Fluorescent in situ hybridizatio...

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Veröffentlicht in:	The Journal of infectious diseases 2006-04, Vol.193 (7), p.912-916
Hauptverfasser:	Clark, Duncan A., Nacheva, Elisabeth P., Leong, Hoe Nam, Brazma, Diana, Li, Ying Ting, Tsao, Edward H. F., Buyck, Hubertus C. E., Atkinson, Claire E., Lawson, Heather M., Potter, Michael N., Griffiths, Paul D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Blood Chromosomes Chromosomes, Human - virology DNA, Viral - analysis DNA, Viral - genetics Female Fundamental and applied biological sciences. Psychology Hematopoietic Stem Cell Transplantation Herpesviridae Herpesvirus 6, Human - genetics Herpesvirus 6, Human - isolation & purification Human herpesvirus 6 Humans In Situ Hybridization, Fluorescence Infections Infectious diseases Leukemia, Myeloid, Acute - therapy Male Medical sciences Microbiology Middle Aged Polymerase chain reaction Proviruses - genetics Roseolovirus Infections - transmission Roseolovirus Infections - virology Stem cells Transplantation Viral Load Virus Integration Viruses
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