KALRN Rare and Common Variants and Susceptibility to Ischemic Stroke in Chinese Han Population

Stroke is the second most common cause of mortality worldwide, and it is a major cause of physical disability. Several genome-wide association studies have yielded numerous common variants which increase the risk of ischemic stroke, including the Kalirin-coding gene, KALRN. KALRN strongly associates...

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Veröffentlicht in:	Neuromolecular medicine 2015-09, Vol.17 (3), p.241-250
Hauptverfasser:	Dang, Meizheng, Wang, Zhenzhen, Zhang, Ruyou, Li, Xiaoying, Peng, Yanqing, Han, Xuesong, Sun, Litao, Tian, Jiawei
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alcohol Drinking - epidemiology Alleles Alternative Splicing Asian Continental Ancestry Group - genetics Asian Continental Ancestry Group - statistics & numerical data Biomedical and Life Sciences Biomedicine Brain Ischemia - ethnology Brain Ischemia - genetics China - epidemiology Comorbidity Diabetes Mellitus - epidemiology Dyslipidemias - epidemiology Ethnic Groups - genetics Ethnic Groups - statistics & numerical data Female Gene Frequency Genome-Wide Association Study Genotype Guanine Nucleotide Exchange Factors - genetics Humans Hypertension - epidemiology Internal Medicine Male Middle Aged Neurology Neurosciences Original Paper Polymorphism, Single Nucleotide Protein-Serine-Threonine Kinases - genetics Risk Factors Smoking - epidemiology Stroke, Lacunar - ethnology Stroke, Lacunar - genetics
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