Safety Assessment of Alkyl Esters as Used in Cosmetics
The Cosmetic Ingredient Review Expert Panel (Panel) assessed the safety of 237 alkyl esters for use in cosmetics. The alkyl esters included in this assessment have a variety of reported functions in cosmetics, with skin-conditioning agent being the most common function. The Panel reviewed available...
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| Veröffentlicht in: | International journal of toxicology 2015-09, Vol.34 (2_suppl), p.5S-69S |
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| container_end_page | 69S |
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| container_issue | 2_suppl |
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| container_title | International journal of toxicology |
| container_volume | 34 |
| creator | Fiume, Monice M. Heldreth, Bart A. Bergfeld, Wilma F. Belsito, Donald V. Hill, Ronald A. Klaassen, Curtis D. Liebler, Daniel C. Marks, James G. Shank, Ronald C. Slaga, Thomas J. Snyder, Paul W. Andersen, F. Alan |
| description | The Cosmetic Ingredient Review Expert Panel (Panel) assessed the safety of 237 alkyl esters for use in cosmetics. The alkyl esters included in this assessment have a variety of reported functions in cosmetics, with skin-conditioning agent being the most common function. The Panel reviewed available animal and clinical data in making its determination of safety on these ingredients, and where there were data gaps, similarity in structure, properties, functions, and uses of these ingredients allowed for extrapolation of the available toxicological data to assess the safety of the entire group. The Panel concluded that these ingredients are safe in cosmetic formulations in the present practices of use and concentration when formulated to be nonirritating. |
| doi_str_mv | 10.1177/1091581815594027 |
| format | Article |
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The Panel concluded that these ingredients are safe in cosmetic formulations in the present practices of use and concentration when formulated to be nonirritating.</description><identifier>ISSN: 1091-5818</identifier><identifier>EISSN: 1092-874X</identifier><identifier>DOI: 10.1177/1091581815594027</identifier><identifier>PMID: 26362120</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Consumer Product Safety ; Cosmetics - adverse effects ; Cosmetics - chemistry ; Esters - adverse effects ; Humans ; Risk Assessment</subject><ispartof>International journal of toxicology, 2015-09, Vol.34 (2_suppl), p.5S-69S</ispartof><rights>The Author(s) 2015</rights><rights>The Author(s) 2015.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c403t-545524862ac629f04f9cad3c8b8e652c8f7f16dcf4acf4452cf72cefb49055563</citedby><cites>FETCH-LOGICAL-c403t-545524862ac629f04f9cad3c8b8e652c8f7f16dcf4acf4452cf72cefb49055563</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/1091581815594027$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/1091581815594027$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21798,27901,27902,43597,43598</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26362120$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fiume, Monice M.</creatorcontrib><creatorcontrib>Heldreth, Bart A.</creatorcontrib><creatorcontrib>Bergfeld, Wilma F.</creatorcontrib><creatorcontrib>Belsito, Donald V.</creatorcontrib><creatorcontrib>Hill, Ronald A.</creatorcontrib><creatorcontrib>Klaassen, Curtis D.</creatorcontrib><creatorcontrib>Liebler, Daniel C.</creatorcontrib><creatorcontrib>Marks, James G.</creatorcontrib><creatorcontrib>Shank, Ronald C.</creatorcontrib><creatorcontrib>Slaga, Thomas J.</creatorcontrib><creatorcontrib>Snyder, Paul W.</creatorcontrib><creatorcontrib>Andersen, F. Alan</creatorcontrib><title>Safety Assessment of Alkyl Esters as Used in Cosmetics</title><title>International journal of toxicology</title><addtitle>Int J Toxicol</addtitle><description>The Cosmetic Ingredient Review Expert Panel (Panel) assessed the safety of 237 alkyl esters for use in cosmetics. The alkyl esters included in this assessment have a variety of reported functions in cosmetics, with skin-conditioning agent being the most common function. The Panel reviewed available animal and clinical data in making its determination of safety on these ingredients, and where there were data gaps, similarity in structure, properties, functions, and uses of these ingredients allowed for extrapolation of the available toxicological data to assess the safety of the entire group. The Panel concluded that these ingredients are safe in cosmetic formulations in the present practices of use and concentration when formulated to be nonirritating.</description><subject>Consumer Product Safety</subject><subject>Cosmetics - adverse effects</subject><subject>Cosmetics - chemistry</subject><subject>Esters - adverse effects</subject><subject>Humans</subject><subject>Risk Assessment</subject><issn>1091-5818</issn><issn>1092-874X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kD1PAzEMhiMEoqWwM6GMLAdJLl83VlULSJUYoBJblOYSdOU-Snw39N-T0sKAxGDZsh-_ll-Erim5o1Spe0oKKjTVVIiCE6ZO0Di1WKYVfzv9rmm2n4_QBcCGECKVoOdoxGQuGWVkjOSLDb7f4SmAB2h82-Mu4Gn9savxHHofAVvAK_Alrlo86xLSVw4u0VmwNfirY56g1WL-OnvMls8PT7PpMnOc5H0muBCMa8msk6wIhIfC2TJ3eq29FMzpoAKVpQvcpuCpExRzPqx5QYQQMp-g24PuNnafg4feNBU4X9e29d0AhirK0oVC5AklB9TFDiD6YLaxamzcGUrM3i3z1620cnNUH9aNL38XfuxJQHYAwL57s-mG2KZv_xf8Agn-b_0</recordid><startdate>20150901</startdate><enddate>20150901</enddate><creator>Fiume, Monice M.</creator><creator>Heldreth, Bart A.</creator><creator>Bergfeld, Wilma F.</creator><creator>Belsito, Donald V.</creator><creator>Hill, Ronald A.</creator><creator>Klaassen, Curtis D.</creator><creator>Liebler, Daniel C.</creator><creator>Marks, James G.</creator><creator>Shank, Ronald C.</creator><creator>Slaga, Thomas J.</creator><creator>Snyder, Paul W.</creator><creator>Andersen, F. 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Alan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Safety Assessment of Alkyl Esters as Used in Cosmetics</atitle><jtitle>International journal of toxicology</jtitle><addtitle>Int J Toxicol</addtitle><date>2015-09-01</date><risdate>2015</risdate><volume>34</volume><issue>2_suppl</issue><spage>5S</spage><epage>69S</epage><pages>5S-69S</pages><issn>1091-5818</issn><eissn>1092-874X</eissn><abstract>The Cosmetic Ingredient Review Expert Panel (Panel) assessed the safety of 237 alkyl esters for use in cosmetics. The alkyl esters included in this assessment have a variety of reported functions in cosmetics, with skin-conditioning agent being the most common function. 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| fulltext | fulltext |
| identifier | ISSN: 1091-5818 |
| ispartof | International journal of toxicology, 2015-09, Vol.34 (2_suppl), p.5S-69S |
| issn | 1091-5818 1092-874X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1712524953 |
| source | SAGE Complete A-Z List; MEDLINE; Alma/SFX Local Collection |
| subjects | Consumer Product Safety Cosmetics - adverse effects Cosmetics - chemistry Esters - adverse effects Humans Risk Assessment |
| title | Safety Assessment of Alkyl Esters as Used in Cosmetics |
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