Asymmetries in kinesin-2 and cytoplasmic dynein contributions to melanosome transport

•We studied the collective action of kinesin-2 and dynein during melanosome transport.•The stiffness of the motor complex linking organelles to microtubules was determined.•The stiffness was obtained from fluctuations perpendicular to the transport direction.•The stiffness and organelle speed depend...

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Veröffentlicht in:	FEBS letters 2015-09, Vol.589 (19), p.2763-2768
Hauptverfasser:	De Rossi, María Cecilia, De Rossi, María Emilia, Sued, Mariela, Rodríguez, Daniela, Bruno, Luciana, Levi, Valeria
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport Cytoplasmic Dyneins - metabolism effective elastic constant Intracellular transport Kinesin - metabolism Melanosomes - metabolism Molecular motors optical radius r op Single particle tracking SPT Xenopus laevis - metabolism Xenopus laevis melanophores Xenopus Proteins - metabolism
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