Role of the Putative Zinc Finger Domain of Saccharomyces cerevisiae DNA Polymerase ε in DNA Replication and the S/M Checkpoint Pathway

It has been proposed that C-terminal motifs of the catalytic subunit of budding yeast polymerase (pol) ε (POL2) couple DNA replication to the S/M checkpoint (Navas, T. A., Zheng, Z., and Elledge, S. J. (1995) Cell80, 29–39). Scanning deletion analysis of the C terminus reveals that 20 amino acid res...

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Veröffentlicht in:	The Journal of biological chemistry 1998-11, Vol.273 (45), p.30046-30055
Hauptverfasser:	Dua, Rajiv, Levy, Daniel L., Campbell, Judith L.
Format:	Artikel
Sprache:	eng
Schlagworte:	ACTIVIDAD ENZIMATICA ACTIVITE ENZYMATIQUE AMIDAS AMIDE AMIDES Base Sequence CELL CYCLE CELL DIVISION DELETIONS DIVISION CELLULAIRE DIVISION CELULAR DNA BINDING MOTIFS DNA Polymerase II - genetics DNA Polymerase II - metabolism DNA Primers DNA Replication ENZYMIC ACTIVITY HYDROXYCARBAMIDE INTERPHASE METHYL METHANESULFONATE MITOSE MITOSIS MMS MUTACION Mutagenesis, Site-Directed MUTANT MUTANTES MUTANTS MUTATION REGULATION REPLICACION REPLICATION S Phase SACCHAROMYCES CEREVISIAE Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - enzymology SUSCEPTIBILITY TARGETED MUTAGENESIS TRANSFERASAS TRANSFERASE TRANSFERASES Zinc Fingers
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