Interleukin-1 beta-induced expression of the prostaglandin E sub(2)-receptor subtype EP3 in U373 astrocytoma cells depends on protein kinase C and nuclear factor-kappaB

Both interleukin-1 beta (IL-1 beta ) and prostaglandins (PGs) are important mediators of physiological and pathophysiological processes in the brain. PGE sub(2) exerts its effects by binding to four different types of PGE sub(2) receptors named EP1-EP4. EP3 has found to be expressed in neurons, wher...

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Veröffentlicht in:Journal of neurochemistry 2006-02, Vol.96 (3), p.680-693
Hauptverfasser: Waschbisch, Anne, Fiebich, Bernd L, Akundi, Ravi Shankar, Schmitz, MLienhard, Hoozemans, Jeroen JM, Candelario-Jalil, Eduardo, Virtainen, Nina, Veerhuis, Robert, Slawik, Helen, Yrjaenheikki, Juha, Huell, Michael
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Sprache:eng
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