Long-term analysis of colonic aberrant crypt formation after treatment of Sprague-Dawley rats with azoxymethane

Human colon cancer is a multistage disease which has been shown to have a number of well‐defined histological and genetic events. This knowledge has identified a series of stages in the development of colon cancer in which dietary components and chemicals may play either a beneficial or detrimental...

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Veröffentlicht in:	Teratogenesis, carcinogenesis, and mutagenesis carcinogenesis, and mutagenesis, 1998, Vol.18 (4), p.183-197
Hauptverfasser:	Davies, M. J., Rumsby, P. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	aberrant crypt foci Animals Azoxymethane - toxicity Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Carcinogens - toxicity Chemical agents colon cancer Colonic Neoplasms - chemically induced Colonic Neoplasms - genetics Male Medical sciences multistage disease Mutation oncogene Polymorphism, Single-Stranded Conformational Precancerous Conditions - chemically induced Precancerous Conditions - genetics Rats Rats, Sprague-Dawley Tumors tumour suppressor genes
Online-Zugang:	Volltext
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