Clinical and sociodemographic correlates of severe insomnia in psychotropic drug-free, Asian outpatients with major depressive disorder
Abstract Background Little has been known regarding the correlates of severe insomnia in major depressive disorder (MDD). This post-hoc analysis aimed to examine the sociodemographic and clinical correlates of severe insomnia in psychotropic drug-free, Asian adult outpatients with MDD. Methods Parti...
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| Veröffentlicht in: | Journal of affective disorders 2015-11, Vol.186, p.26-31 |
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| creator | Srisurapanont, Manit Likhitsathian, Surinporn Chua, Hong Choon Udomratn, Pichet Chang, Sungman Maneeton, Narong Maneeton, Benchaluk Chen, Chia-Hui Shih-Yen Chan, Edwin Bautista, Dianne Bin Sulaiman, Ahmad Hatim |
| description | Abstract Background Little has been known regarding the correlates of severe insomnia in major depressive disorder (MDD). This post-hoc analysis aimed to examine the sociodemographic and clinical correlates of severe insomnia in psychotropic drug-free, Asian adult outpatients with MDD. Methods Participants were psychotropic drug-free patients with MDD, aged 18–65 years. By using the Symptom Checklist-90 Items, Revised (SCL-90-R), a score of 4 (severe distress) on any one of three insomnia items was defined as severe insomnia. Other measures included the Montgomery–Asberg Depression Rating Scale (MADRS), the Fatigue Severity Scale (FSS), the nine psychopathology subscales of SCL-90-R, the Physical and Mental Component Summaries of Short Form Health Survey (SF-36 PCS and SF-36 MCS), and the Sheehan Disability Scale (SDS). Results Of 528 participants, their mean age being 39.5 (SD=13.26) years, 64.2% were females, and 239 (45.3%) had severe insomnia. The logistic regression model revealed that low educational qualifications (less than secondary school completion), high SCL-90- R Depression scores, high SCL-90-R Anxiety scores, and low SF-36 PCS scores were independently correlated with severe insomnia ( p 's |
| doi_str_mv | 10.1016/j.jad.2015.06.032 |
| format | Article |
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This post-hoc analysis aimed to examine the sociodemographic and clinical correlates of severe insomnia in psychotropic drug-free, Asian adult outpatients with MDD. Methods Participants were psychotropic drug-free patients with MDD, aged 18–65 years. By using the Symptom Checklist-90 Items, Revised (SCL-90-R), a score of 4 (severe distress) on any one of three insomnia items was defined as severe insomnia. Other measures included the Montgomery–Asberg Depression Rating Scale (MADRS), the Fatigue Severity Scale (FSS), the nine psychopathology subscales of SCL-90-R, the Physical and Mental Component Summaries of Short Form Health Survey (SF-36 PCS and SF-36 MCS), and the Sheehan Disability Scale (SDS). Results Of 528 participants, their mean age being 39.5 (SD=13.26) years, 64.2% were females, and 239 (45.3%) had severe insomnia. The logistic regression model revealed that low educational qualifications (less than secondary school completion), high SCL-90- R Depression scores, high SCL-90-R Anxiety scores, and low SF-36 PCS scores were independently correlated with severe insomnia ( p 's<.05). Limitations Insomnia was determined only by the patient's distress. Middle insomnia was not assessed. Psychotropic drug-free patients with MDD are not commonly seen in psychiatric practice. Conclusion Severe insomnia is common in patients with MDD. It is closely related with low educational qualification, subjective depression and anxiety severity, and poor physical health. These findings may implicate the treatment of comorbid MDD and severe insomnia, for example, sleep hygiene education, pharmacological treatment.</description><identifier>ISSN: 0165-0327</identifier><identifier>EISSN: 1573-2517</identifier><identifier>DOI: 10.1016/j.jad.2015.06.032</identifier><identifier>PMID: 26226430</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Adolescent ; Adult ; Aged ; Anxiety Disorders - complications ; Anxiety Disorders - psychology ; Asian ; Asian Continental Ancestry Group - psychology ; Asian Continental Ancestry Group - statistics & numerical data ; Depression - complications ; Depression - psychology ; Depressive Disorder, Major - complications ; Depressive Disorder, Major - psychology ; Depressive disorders ; Educational Status ; Female ; Humans ; Insomnia ; Logistic Models ; Male ; Middle Aged ; Outpatients - psychology ; Outpatients - statistics & numerical data ; Psychiatric Status Rating Scales - statistics & numerical data ; Psychiatry ; Psychotropic Drugs - therapeutic use ; SCL-90-R ; Sleep Initiation and Maintenance Disorders - complications ; Sleep Initiation and Maintenance Disorders - psychology ; Subjective ; Young Adult</subject><ispartof>Journal of affective disorders, 2015-11, Vol.186, p.26-31</ispartof><rights>Elsevier B.V.</rights><rights>2015 Elsevier B.V.</rights><rights>Copyright © 2015 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-e787839b8af9e4475f94aabbd8f4e701707cea1037396c41e175c82c9f94f7a43</citedby><cites>FETCH-LOGICAL-c408t-e787839b8af9e4475f94aabbd8f4e701707cea1037396c41e175c82c9f94f7a43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jad.2015.06.032$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26226430$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Srisurapanont, Manit</creatorcontrib><creatorcontrib>Likhitsathian, Surinporn</creatorcontrib><creatorcontrib>Chua, Hong Choon</creatorcontrib><creatorcontrib>Udomratn, Pichet</creatorcontrib><creatorcontrib>Chang, Sungman</creatorcontrib><creatorcontrib>Maneeton, Narong</creatorcontrib><creatorcontrib>Maneeton, Benchaluk</creatorcontrib><creatorcontrib>Chen, Chia-Hui</creatorcontrib><creatorcontrib>Shih-Yen Chan, Edwin</creatorcontrib><creatorcontrib>Bautista, Dianne</creatorcontrib><creatorcontrib>Bin Sulaiman, Ahmad Hatim</creatorcontrib><title>Clinical and sociodemographic correlates of severe insomnia in psychotropic drug-free, Asian outpatients with major depressive disorder</title><title>Journal of affective disorders</title><addtitle>J Affect Disord</addtitle><description>Abstract Background Little has been known regarding the correlates of severe insomnia in major depressive disorder (MDD). This post-hoc analysis aimed to examine the sociodemographic and clinical correlates of severe insomnia in psychotropic drug-free, Asian adult outpatients with MDD. Methods Participants were psychotropic drug-free patients with MDD, aged 18–65 years. By using the Symptom Checklist-90 Items, Revised (SCL-90-R), a score of 4 (severe distress) on any one of three insomnia items was defined as severe insomnia. Other measures included the Montgomery–Asberg Depression Rating Scale (MADRS), the Fatigue Severity Scale (FSS), the nine psychopathology subscales of SCL-90-R, the Physical and Mental Component Summaries of Short Form Health Survey (SF-36 PCS and SF-36 MCS), and the Sheehan Disability Scale (SDS). Results Of 528 participants, their mean age being 39.5 (SD=13.26) years, 64.2% were females, and 239 (45.3%) had severe insomnia. The logistic regression model revealed that low educational qualifications (less than secondary school completion), high SCL-90- R Depression scores, high SCL-90-R Anxiety scores, and low SF-36 PCS scores were independently correlated with severe insomnia ( p 's<.05). Limitations Insomnia was determined only by the patient's distress. Middle insomnia was not assessed. Psychotropic drug-free patients with MDD are not commonly seen in psychiatric practice. Conclusion Severe insomnia is common in patients with MDD. It is closely related with low educational qualification, subjective depression and anxiety severity, and poor physical health. These findings may implicate the treatment of comorbid MDD and severe insomnia, for example, sleep hygiene education, pharmacological treatment.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Anxiety Disorders - complications</subject><subject>Anxiety Disorders - psychology</subject><subject>Asian</subject><subject>Asian Continental Ancestry Group - psychology</subject><subject>Asian Continental Ancestry Group - statistics & numerical data</subject><subject>Depression - complications</subject><subject>Depression - psychology</subject><subject>Depressive Disorder, Major - complications</subject><subject>Depressive Disorder, Major - psychology</subject><subject>Depressive disorders</subject><subject>Educational Status</subject><subject>Female</subject><subject>Humans</subject><subject>Insomnia</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Outpatients - psychology</subject><subject>Outpatients - statistics & numerical data</subject><subject>Psychiatric Status Rating Scales - statistics & numerical data</subject><subject>Psychiatry</subject><subject>Psychotropic Drugs - therapeutic use</subject><subject>SCL-90-R</subject><subject>Sleep Initiation and Maintenance Disorders - complications</subject><subject>Sleep Initiation and Maintenance Disorders - psychology</subject><subject>Subjective</subject><subject>Young Adult</subject><issn>0165-0327</issn><issn>1573-2517</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kk2r1DAUhoMo3rlXf4AbydKFrflomxZBuAxeFS64UNchk5zeSW2bmpOOzC_wb5thRhcuXCWE530hzzmEvOCs5Iw3b4ZyMK4UjNcla0omxSOy4bWShai5ekw2mamL_KyuyDXiwBhrOsWekivRCNFUkm3Ir-3oZ2_NSM3sKAbrg4MpPESz7L2lNsQIo0mANPQU4QARqJ8xTLM3-UIXPNp9SDEsmXZxfSj6CPCa3qI3Mw1rWkzyMCekP33a08kMIVIHSwREfwDqPIboID4jT3ozIjy_nDfk2937r9uPxf3nD5-2t_eFrVibClCtamW3a03fQVWpuu8qY3Y71_YVKMYVUxYMZ1LJrrEVB65q2wrbZa5XppI35NW5d4nhxwqY9OTRwjiaGcKKmivOulZ0XZNRfkZtDIgRer1EP5l41Jzpk3896Oxfn_xr1ugsOmdeXurX3QTub-KP8Ay8PQOQP3nwEDXa7MeC8xFs0i74_9a_-ydtL-P7DkfAIaxxzvY01yg0019OC3CaP68lE6qS8jcorq2H</recordid><startdate>20151101</startdate><enddate>20151101</enddate><creator>Srisurapanont, Manit</creator><creator>Likhitsathian, Surinporn</creator><creator>Chua, Hong Choon</creator><creator>Udomratn, Pichet</creator><creator>Chang, Sungman</creator><creator>Maneeton, Narong</creator><creator>Maneeton, Benchaluk</creator><creator>Chen, Chia-Hui</creator><creator>Shih-Yen Chan, Edwin</creator><creator>Bautista, Dianne</creator><creator>Bin Sulaiman, Ahmad Hatim</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20151101</creationdate><title>Clinical and sociodemographic correlates of severe insomnia in psychotropic drug-free, Asian outpatients with major depressive disorder</title><author>Srisurapanont, Manit ; Likhitsathian, Surinporn ; Chua, Hong Choon ; Udomratn, Pichet ; Chang, Sungman ; Maneeton, Narong ; Maneeton, Benchaluk ; Chen, Chia-Hui ; Shih-Yen Chan, Edwin ; Bautista, Dianne ; Bin Sulaiman, Ahmad Hatim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-e787839b8af9e4475f94aabbd8f4e701707cea1037396c41e175c82c9f94f7a43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Anxiety Disorders - complications</topic><topic>Anxiety Disorders - psychology</topic><topic>Asian</topic><topic>Asian Continental Ancestry Group - psychology</topic><topic>Asian Continental Ancestry Group - statistics & numerical data</topic><topic>Depression - complications</topic><topic>Depression - psychology</topic><topic>Depressive Disorder, Major - complications</topic><topic>Depressive Disorder, Major - psychology</topic><topic>Depressive disorders</topic><topic>Educational Status</topic><topic>Female</topic><topic>Humans</topic><topic>Insomnia</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Outpatients - psychology</topic><topic>Outpatients - statistics & numerical data</topic><topic>Psychiatric Status Rating Scales - statistics & numerical data</topic><topic>Psychiatry</topic><topic>Psychotropic Drugs - therapeutic use</topic><topic>SCL-90-R</topic><topic>Sleep Initiation and Maintenance Disorders - complications</topic><topic>Sleep Initiation and Maintenance Disorders - psychology</topic><topic>Subjective</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Srisurapanont, Manit</creatorcontrib><creatorcontrib>Likhitsathian, Surinporn</creatorcontrib><creatorcontrib>Chua, Hong Choon</creatorcontrib><creatorcontrib>Udomratn, Pichet</creatorcontrib><creatorcontrib>Chang, Sungman</creatorcontrib><creatorcontrib>Maneeton, Narong</creatorcontrib><creatorcontrib>Maneeton, Benchaluk</creatorcontrib><creatorcontrib>Chen, Chia-Hui</creatorcontrib><creatorcontrib>Shih-Yen Chan, Edwin</creatorcontrib><creatorcontrib>Bautista, Dianne</creatorcontrib><creatorcontrib>Bin Sulaiman, Ahmad Hatim</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of affective disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Srisurapanont, Manit</au><au>Likhitsathian, Surinporn</au><au>Chua, Hong Choon</au><au>Udomratn, Pichet</au><au>Chang, Sungman</au><au>Maneeton, Narong</au><au>Maneeton, Benchaluk</au><au>Chen, Chia-Hui</au><au>Shih-Yen Chan, Edwin</au><au>Bautista, Dianne</au><au>Bin Sulaiman, Ahmad Hatim</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical and sociodemographic correlates of severe insomnia in psychotropic drug-free, Asian outpatients with major depressive disorder</atitle><jtitle>Journal of affective disorders</jtitle><addtitle>J Affect Disord</addtitle><date>2015-11-01</date><risdate>2015</risdate><volume>186</volume><spage>26</spage><epage>31</epage><pages>26-31</pages><issn>0165-0327</issn><eissn>1573-2517</eissn><abstract>Abstract Background Little has been known regarding the correlates of severe insomnia in major depressive disorder (MDD). This post-hoc analysis aimed to examine the sociodemographic and clinical correlates of severe insomnia in psychotropic drug-free, Asian adult outpatients with MDD. Methods Participants were psychotropic drug-free patients with MDD, aged 18–65 years. By using the Symptom Checklist-90 Items, Revised (SCL-90-R), a score of 4 (severe distress) on any one of three insomnia items was defined as severe insomnia. Other measures included the Montgomery–Asberg Depression Rating Scale (MADRS), the Fatigue Severity Scale (FSS), the nine psychopathology subscales of SCL-90-R, the Physical and Mental Component Summaries of Short Form Health Survey (SF-36 PCS and SF-36 MCS), and the Sheehan Disability Scale (SDS). Results Of 528 participants, their mean age being 39.5 (SD=13.26) years, 64.2% were females, and 239 (45.3%) had severe insomnia. The logistic regression model revealed that low educational qualifications (less than secondary school completion), high SCL-90- R Depression scores, high SCL-90-R Anxiety scores, and low SF-36 PCS scores were independently correlated with severe insomnia ( p 's<.05). Limitations Insomnia was determined only by the patient's distress. Middle insomnia was not assessed. Psychotropic drug-free patients with MDD are not commonly seen in psychiatric practice. Conclusion Severe insomnia is common in patients with MDD. It is closely related with low educational qualification, subjective depression and anxiety severity, and poor physical health. These findings may implicate the treatment of comorbid MDD and severe insomnia, for example, sleep hygiene education, pharmacological treatment.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>26226430</pmid><doi>10.1016/j.jad.2015.06.032</doi><tpages>6</tpages></addata></record> |
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| subjects | Adolescent Adult Aged Anxiety Disorders - complications Anxiety Disorders - psychology Asian Asian Continental Ancestry Group - psychology Asian Continental Ancestry Group - statistics & numerical data Depression - complications Depression - psychology Depressive Disorder, Major - complications Depressive Disorder, Major - psychology Depressive disorders Educational Status Female Humans Insomnia Logistic Models Male Middle Aged Outpatients - psychology Outpatients - statistics & numerical data Psychiatric Status Rating Scales - statistics & numerical data Psychiatry Psychotropic Drugs - therapeutic use SCL-90-R Sleep Initiation and Maintenance Disorders - complications Sleep Initiation and Maintenance Disorders - psychology Subjective Young Adult |
| title | Clinical and sociodemographic correlates of severe insomnia in psychotropic drug-free, Asian outpatients with major depressive disorder |
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