A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-κB

The signaling pathway through which ionizing radiation induces NF-κB activation is not fully understood. IκB-α, an inhibitory protein of NF-κB mediates the activation of NF-κB in response to various stimuli, including cytokines, mitogens, oxidants and other stresses. We have now identified an ionizi...

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