Isolated fibromuscular dysplasia of the coronary ostium: a rare cause of sudden death. Case report and review of the literature
Abstract We present a unique case of sudden death in a 21-year-old man with history of cocaine use and a solitary fibromuscular dysplastic lesion completely occluding the left coronary artery ostium. We document intimal proliferation of myofibroblasts at the opening of the left coronary ostium witho...
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| Veröffentlicht in: | Cardiovascular pathology 2015-09, Vol.24 (5), p.327-331 |
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| container_title | Cardiovascular pathology |
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| creator | Garcia, Rafael A deRoux, Stephen J Axiotis, Constantine A |
| description | Abstract We present a unique case of sudden death in a 21-year-old man with history of cocaine use and a solitary fibromuscular dysplastic lesion completely occluding the left coronary artery ostium. We document intimal proliferation of myofibroblasts at the opening of the left coronary ostium without other concomitant lesions. This report discusses the gross and histologic features of the lesion, explores in careful detail the possible etiologies, and gives a comprehensive literature review of isolated coronary ostial fibromuscular dysplasia presenting with sudden death. |
| doi_str_mv | 10.1016/j.carpath.2015.04.006 |
| format | Article |
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This report discusses the gross and histologic features of the lesion, explores in careful detail the possible etiologies, and gives a comprehensive literature review of isolated coronary ostial fibromuscular dysplasia presenting with sudden death.</description><identifier>ISSN: 1054-8807</identifier><identifier>EISSN: 1879-1336</identifier><identifier>DOI: 10.1016/j.carpath.2015.04.006</identifier><identifier>PMID: 25953280</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Cocaine ; Coronary ostium ; Coronary Vessels - pathology ; Death, Sudden, Cardiac - etiology ; Death, Sudden, Cardiac - pathology ; Fibromuscular dysplasia ; Fibromuscular Dysplasia - complications ; Fibromuscular Dysplasia - pathology ; Humans ; Male ; Pathology ; Sudden death ; Young Adult</subject><ispartof>Cardiovascular pathology, 2015-09, Vol.24 (5), p.327-331</ispartof><rights>Elsevier Inc.</rights><rights>2015 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c490t-ac4d9c763f36217a36596af0f94ff42af13cde8200e92c5278ba4a3b2b06db713</citedby><cites>FETCH-LOGICAL-c490t-ac4d9c763f36217a36596af0f94ff42af13cde8200e92c5278ba4a3b2b06db713</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1054880715000538$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25953280$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Garcia, Rafael A</creatorcontrib><creatorcontrib>deRoux, Stephen J</creatorcontrib><creatorcontrib>Axiotis, Constantine A</creatorcontrib><title>Isolated fibromuscular dysplasia of the coronary ostium: a rare cause of sudden death. 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This report discusses the gross and histologic features of the lesion, explores in careful detail the possible etiologies, and gives a comprehensive literature review of isolated coronary ostial fibromuscular dysplasia presenting with sudden death.</description><subject>Cocaine</subject><subject>Coronary ostium</subject><subject>Coronary Vessels - pathology</subject><subject>Death, Sudden, Cardiac - etiology</subject><subject>Death, Sudden, Cardiac - pathology</subject><subject>Fibromuscular dysplasia</subject><subject>Fibromuscular Dysplasia - complications</subject><subject>Fibromuscular Dysplasia - pathology</subject><subject>Humans</subject><subject>Male</subject><subject>Pathology</subject><subject>Sudden death</subject><subject>Young Adult</subject><issn>1054-8807</issn><issn>1879-1336</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkk2P1DAMhisEYj_gJ4By5NLiNEk_OIDQCJaVVuIAnCM3cbUZ2mZIGtCc-OukmlkOXDjFsl6_th-nKF5wqDjw5vW-MhgOuN5XNXBVgawAmkfFJe_avuRCNI9zDEqWXQftRXEV4x4AOinl0-KiVr0SdQeXxe_b6CdcybLRDcHPKZo0YWD2GA8TRofMj2y9J2Z88AuGI_NxdWl-w5AFDDmPKdImislaWpilbSa2w5wNdPBhZbjYHP509OvBbHIrBVxToGfFkxGnSM_P73Xx7eOHr7tP5d3nm9vd-7vSyB7WEo20vWkbMYqm5i2KRvUNjjD2chxljSMXxlJXA1BfG1W33YASxVAP0Nih5eK6eHXyPQT_I1Fc9eyioWnChXyKmrccGtW2CrJUnaQm-BgDjfoQ3JxX1xz0xl7v9Zm93thrkDqzz3Uvzy3SMJP9W_UAOwvenQSUF804go7G0WLIukBm1da7_7Z4-4-DmdziDE7f6Uhx71NYMkXNdaw16C_bB9juz1W-vRKd-AOwp66A</recordid><startdate>20150901</startdate><enddate>20150901</enddate><creator>Garcia, Rafael A</creator><creator>deRoux, Stephen J</creator><creator>Axiotis, Constantine A</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150901</creationdate><title>Isolated fibromuscular dysplasia of the coronary ostium: a rare cause of sudden death. 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Case report and review of the literature</atitle><jtitle>Cardiovascular pathology</jtitle><addtitle>Cardiovasc Pathol</addtitle><date>2015-09-01</date><risdate>2015</risdate><volume>24</volume><issue>5</issue><spage>327</spage><epage>331</epage><pages>327-331</pages><issn>1054-8807</issn><eissn>1879-1336</eissn><abstract>Abstract We present a unique case of sudden death in a 21-year-old man with history of cocaine use and a solitary fibromuscular dysplastic lesion completely occluding the left coronary artery ostium. We document intimal proliferation of myofibroblasts at the opening of the left coronary ostium without other concomitant lesions. 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| fulltext | fulltext |
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| ispartof | Cardiovascular pathology, 2015-09, Vol.24 (5), p.327-331 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Cocaine Coronary ostium Coronary Vessels - pathology Death, Sudden, Cardiac - etiology Death, Sudden, Cardiac - pathology Fibromuscular dysplasia Fibromuscular Dysplasia - complications Fibromuscular Dysplasia - pathology Humans Male Pathology Sudden death Young Adult |
| title | Isolated fibromuscular dysplasia of the coronary ostium: a rare cause of sudden death. Case report and review of the literature |
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