Platelet to Lymphocyte Ratio Can be a Predictor of Infarct-Related Artery Patency in Patients With ST-Segment Elevation Myocardial Infarction
Patency of infarct-related artery (IRA) in patients with ST-segment elevation myocardial infarction (STEMI) before primary percutaneous coronary intervention (pPCI) is associated with lower mortality and better clinical outcome. However, there were little data regarding the predictors of IRA patency...
Gespeichert in:
| Veröffentlicht in: | Angiology 2015-10, Vol.66 (9), p.831-836 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 836 |
|---|---|
| container_issue | 9 |
| container_start_page | 831 |
| container_title | Angiology |
| container_volume | 66 |
| creator | Yayla, Çağrı Akboğa, Mehmet Kadri Canpolat, Uğur Akyel, Ahmet Yayla, Kadriye Gayretli Doğan, Mehmet Yeter, Ekrem Aydoğdu, Sinan |
| description | Patency of infarct-related artery (IRA) in patients with ST-segment elevation myocardial infarction (STEMI) before primary percutaneous coronary intervention (pPCI) is associated with lower mortality and better clinical outcome. However, there were little data regarding the predictors of IRA patency before pPCI in the setting of STEMI. We aimed to assess the association of platelet to lymphocyte ratio (PLR) with IRA patency in STEMI. A total of 452 patients were enrolled and categorized as occluded or patent IRA. Patency IRA was assessed by the thrombolysis in myocardial infarction (TIMI) flow grade. Blood samples were obtained on admission to calculate PLR. Of all patients, 92 (20.4%) patients revealed pre-pPCI TIMI 3 flow in IRA. The PLR was significantly higher in occluded IRA group (138.4 ± 51.4 vs 95.4 ± 43.5, P < .001). Glucose, troponin I, and neutrophil to lymphocyte ratio (NLR) levels were also higher in occluded IRA group (P < .05). Multivariate regression analysis demonstrated the PLR (odds ratio [OR]: 0.987; 95% confidence interval [CI]: 0.978-0.995, P = .002) and NLR (OR: 0.758; 95% CI: 0.584-0.985, P = .038) on admission as independent predictors of IRA patency. In conclusion, a higher PLR is a powerful and independent predictor of IRA patency in patients with STEMI before pPCI. |
| doi_str_mv | 10.1177/0003319715573658 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1710656884</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_0003319715573658</sage_id><sourcerecordid>1710656884</sourcerecordid><originalsourceid>FETCH-LOGICAL-c337t-da50ac03710d52d4c56bb94c59236cb5c75edb1b5ede0d7700dc98a7c8739bcd3</originalsourceid><addsrcrecordid>eNp1kU1LxDAQhoMoun7cPUmOXqpJ0zTtURY_FlZc3BWPJU2mbpe2WZNU6I_wP5uy6kHwksnMvO8DM4PQOSVXlApxTQhhjOaCci5YyrM9NKF5QiLKRbKPJmM7GvtH6Ni5TUg5JekhOoq5oHGckwn6XDTSQwMee4PnQ7tdGzV4wM_S1wZPZYdLwBIvLOhaeWOxqfCsq6RVPnqG0avxjfVgB7wISacGXHfjt4bOO_xa-zVerqIlvLWhgG8b-BjJHX4cjJJW17L54YXqKTqoZOPg7DueoJe729X0IZo_3c-mN_NIMSZ8pCUnUhEmKNE81oniaVnmIeQxS1XJleCgS1qGF4gWghCt8kwKlQmWl0qzE3S5426tee_B-aKtnYKmkR2Y3hU0kFOeZlkSpGQnVdY4Z6EqtrZupR0KSorxCMXfIwTLxTe9L1vQv4afrQdBtBM4-QbFxvS2C9P-D_wCpCWQOg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1710656884</pqid></control><display><type>article</type><title>Platelet to Lymphocyte Ratio Can be a Predictor of Infarct-Related Artery Patency in Patients With ST-Segment Elevation Myocardial Infarction</title><source>MEDLINE</source><source>SAGE Complete A-Z List</source><creator>Yayla, Çağrı ; Akboğa, Mehmet Kadri ; Canpolat, Uğur ; Akyel, Ahmet ; Yayla, Kadriye Gayretli ; Doğan, Mehmet ; Yeter, Ekrem ; Aydoğdu, Sinan</creator><creatorcontrib>Yayla, Çağrı ; Akboğa, Mehmet Kadri ; Canpolat, Uğur ; Akyel, Ahmet ; Yayla, Kadriye Gayretli ; Doğan, Mehmet ; Yeter, Ekrem ; Aydoğdu, Sinan</creatorcontrib><description>Patency of infarct-related artery (IRA) in patients with ST-segment elevation myocardial infarction (STEMI) before primary percutaneous coronary intervention (pPCI) is associated with lower mortality and better clinical outcome. However, there were little data regarding the predictors of IRA patency before pPCI in the setting of STEMI. We aimed to assess the association of platelet to lymphocyte ratio (PLR) with IRA patency in STEMI. A total of 452 patients were enrolled and categorized as occluded or patent IRA. Patency IRA was assessed by the thrombolysis in myocardial infarction (TIMI) flow grade. Blood samples were obtained on admission to calculate PLR. Of all patients, 92 (20.4%) patients revealed pre-pPCI TIMI 3 flow in IRA. The PLR was significantly higher in occluded IRA group (138.4 ± 51.4 vs 95.4 ± 43.5, P < .001). Glucose, troponin I, and neutrophil to lymphocyte ratio (NLR) levels were also higher in occluded IRA group (P < .05). Multivariate regression analysis demonstrated the PLR (odds ratio [OR]: 0.987; 95% confidence interval [CI]: 0.978-0.995, P = .002) and NLR (OR: 0.758; 95% CI: 0.584-0.985, P = .038) on admission as independent predictors of IRA patency. In conclusion, a higher PLR is a powerful and independent predictor of IRA patency in patients with STEMI before pPCI.</description><identifier>ISSN: 0003-3197</identifier><identifier>EISSN: 1940-1574</identifier><identifier>DOI: 10.1177/0003319715573658</identifier><identifier>PMID: 25712290</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Aged ; Biomarkers - blood ; Blood Platelets ; Chi-Square Distribution ; Coronary Angiography ; Coronary Artery Disease - blood ; Coronary Artery Disease - complications ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - physiopathology ; Coronary Circulation ; Coronary Occlusion - blood ; Coronary Occlusion - complications ; Coronary Occlusion - diagnosis ; Coronary Occlusion - physiopathology ; Coronary Vessels - diagnostic imaging ; Coronary Vessels - physiopathology ; Female ; Humans ; Logistic Models ; Lymphocyte Count ; Lymphocytes ; Male ; Middle Aged ; Multivariate Analysis ; Myocardial Infarction - blood ; Myocardial Infarction - diagnosis ; Myocardial Infarction - etiology ; Myocardial Infarction - physiopathology ; Odds Ratio ; Platelet Count ; Predictive Value of Tests ; Retrospective Studies ; Risk Factors ; Turkey ; Vascular Patency</subject><ispartof>Angiology, 2015-10, Vol.66 (9), p.831-836</ispartof><rights>The Author(s) 2015</rights><rights>The Author(s) 2015.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c337t-da50ac03710d52d4c56bb94c59236cb5c75edb1b5ede0d7700dc98a7c8739bcd3</citedby><cites>FETCH-LOGICAL-c337t-da50ac03710d52d4c56bb94c59236cb5c75edb1b5ede0d7700dc98a7c8739bcd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/0003319715573658$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/0003319715573658$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21818,27923,27924,43620,43621</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25712290$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yayla, Çağrı</creatorcontrib><creatorcontrib>Akboğa, Mehmet Kadri</creatorcontrib><creatorcontrib>Canpolat, Uğur</creatorcontrib><creatorcontrib>Akyel, Ahmet</creatorcontrib><creatorcontrib>Yayla, Kadriye Gayretli</creatorcontrib><creatorcontrib>Doğan, Mehmet</creatorcontrib><creatorcontrib>Yeter, Ekrem</creatorcontrib><creatorcontrib>Aydoğdu, Sinan</creatorcontrib><title>Platelet to Lymphocyte Ratio Can be a Predictor of Infarct-Related Artery Patency in Patients With ST-Segment Elevation Myocardial Infarction</title><title>Angiology</title><addtitle>Angiology</addtitle><description>Patency of infarct-related artery (IRA) in patients with ST-segment elevation myocardial infarction (STEMI) before primary percutaneous coronary intervention (pPCI) is associated with lower mortality and better clinical outcome. However, there were little data regarding the predictors of IRA patency before pPCI in the setting of STEMI. We aimed to assess the association of platelet to lymphocyte ratio (PLR) with IRA patency in STEMI. A total of 452 patients were enrolled and categorized as occluded or patent IRA. Patency IRA was assessed by the thrombolysis in myocardial infarction (TIMI) flow grade. Blood samples were obtained on admission to calculate PLR. Of all patients, 92 (20.4%) patients revealed pre-pPCI TIMI 3 flow in IRA. The PLR was significantly higher in occluded IRA group (138.4 ± 51.4 vs 95.4 ± 43.5, P < .001). Glucose, troponin I, and neutrophil to lymphocyte ratio (NLR) levels were also higher in occluded IRA group (P < .05). Multivariate regression analysis demonstrated the PLR (odds ratio [OR]: 0.987; 95% confidence interval [CI]: 0.978-0.995, P = .002) and NLR (OR: 0.758; 95% CI: 0.584-0.985, P = .038) on admission as independent predictors of IRA patency. In conclusion, a higher PLR is a powerful and independent predictor of IRA patency in patients with STEMI before pPCI.</description><subject>Aged</subject><subject>Biomarkers - blood</subject><subject>Blood Platelets</subject><subject>Chi-Square Distribution</subject><subject>Coronary Angiography</subject><subject>Coronary Artery Disease - blood</subject><subject>Coronary Artery Disease - complications</subject><subject>Coronary Artery Disease - diagnosis</subject><subject>Coronary Artery Disease - physiopathology</subject><subject>Coronary Circulation</subject><subject>Coronary Occlusion - blood</subject><subject>Coronary Occlusion - complications</subject><subject>Coronary Occlusion - diagnosis</subject><subject>Coronary Occlusion - physiopathology</subject><subject>Coronary Vessels - diagnostic imaging</subject><subject>Coronary Vessels - physiopathology</subject><subject>Female</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Lymphocyte Count</subject><subject>Lymphocytes</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Myocardial Infarction - blood</subject><subject>Myocardial Infarction - diagnosis</subject><subject>Myocardial Infarction - etiology</subject><subject>Myocardial Infarction - physiopathology</subject><subject>Odds Ratio</subject><subject>Platelet Count</subject><subject>Predictive Value of Tests</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Turkey</subject><subject>Vascular Patency</subject><issn>0003-3197</issn><issn>1940-1574</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU1LxDAQhoMoun7cPUmOXqpJ0zTtURY_FlZc3BWPJU2mbpe2WZNU6I_wP5uy6kHwksnMvO8DM4PQOSVXlApxTQhhjOaCci5YyrM9NKF5QiLKRbKPJmM7GvtH6Ni5TUg5JekhOoq5oHGckwn6XDTSQwMee4PnQ7tdGzV4wM_S1wZPZYdLwBIvLOhaeWOxqfCsq6RVPnqG0avxjfVgB7wISacGXHfjt4bOO_xa-zVerqIlvLWhgG8b-BjJHX4cjJJW17L54YXqKTqoZOPg7DueoJe729X0IZo_3c-mN_NIMSZ8pCUnUhEmKNE81oniaVnmIeQxS1XJleCgS1qGF4gWghCt8kwKlQmWl0qzE3S5426tee_B-aKtnYKmkR2Y3hU0kFOeZlkSpGQnVdY4Z6EqtrZupR0KSorxCMXfIwTLxTe9L1vQv4afrQdBtBM4-QbFxvS2C9P-D_wCpCWQOg</recordid><startdate>20151001</startdate><enddate>20151001</enddate><creator>Yayla, Çağrı</creator><creator>Akboğa, Mehmet Kadri</creator><creator>Canpolat, Uğur</creator><creator>Akyel, Ahmet</creator><creator>Yayla, Kadriye Gayretli</creator><creator>Doğan, Mehmet</creator><creator>Yeter, Ekrem</creator><creator>Aydoğdu, Sinan</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20151001</creationdate><title>Platelet to Lymphocyte Ratio Can be a Predictor of Infarct-Related Artery Patency in Patients With ST-Segment Elevation Myocardial Infarction</title><author>Yayla, Çağrı ; Akboğa, Mehmet Kadri ; Canpolat, Uğur ; Akyel, Ahmet ; Yayla, Kadriye Gayretli ; Doğan, Mehmet ; Yeter, Ekrem ; Aydoğdu, Sinan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c337t-da50ac03710d52d4c56bb94c59236cb5c75edb1b5ede0d7700dc98a7c8739bcd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Aged</topic><topic>Biomarkers - blood</topic><topic>Blood Platelets</topic><topic>Chi-Square Distribution</topic><topic>Coronary Angiography</topic><topic>Coronary Artery Disease - blood</topic><topic>Coronary Artery Disease - complications</topic><topic>Coronary Artery Disease - diagnosis</topic><topic>Coronary Artery Disease - physiopathology</topic><topic>Coronary Circulation</topic><topic>Coronary Occlusion - blood</topic><topic>Coronary Occlusion - complications</topic><topic>Coronary Occlusion - diagnosis</topic><topic>Coronary Occlusion - physiopathology</topic><topic>Coronary Vessels - diagnostic imaging</topic><topic>Coronary Vessels - physiopathology</topic><topic>Female</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Lymphocyte Count</topic><topic>Lymphocytes</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Myocardial Infarction - blood</topic><topic>Myocardial Infarction - diagnosis</topic><topic>Myocardial Infarction - etiology</topic><topic>Myocardial Infarction - physiopathology</topic><topic>Odds Ratio</topic><topic>Platelet Count</topic><topic>Predictive Value of Tests</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Turkey</topic><topic>Vascular Patency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yayla, Çağrı</creatorcontrib><creatorcontrib>Akboğa, Mehmet Kadri</creatorcontrib><creatorcontrib>Canpolat, Uğur</creatorcontrib><creatorcontrib>Akyel, Ahmet</creatorcontrib><creatorcontrib>Yayla, Kadriye Gayretli</creatorcontrib><creatorcontrib>Doğan, Mehmet</creatorcontrib><creatorcontrib>Yeter, Ekrem</creatorcontrib><creatorcontrib>Aydoğdu, Sinan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Angiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yayla, Çağrı</au><au>Akboğa, Mehmet Kadri</au><au>Canpolat, Uğur</au><au>Akyel, Ahmet</au><au>Yayla, Kadriye Gayretli</au><au>Doğan, Mehmet</au><au>Yeter, Ekrem</au><au>Aydoğdu, Sinan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Platelet to Lymphocyte Ratio Can be a Predictor of Infarct-Related Artery Patency in Patients With ST-Segment Elevation Myocardial Infarction</atitle><jtitle>Angiology</jtitle><addtitle>Angiology</addtitle><date>2015-10-01</date><risdate>2015</risdate><volume>66</volume><issue>9</issue><spage>831</spage><epage>836</epage><pages>831-836</pages><issn>0003-3197</issn><eissn>1940-1574</eissn><abstract>Patency of infarct-related artery (IRA) in patients with ST-segment elevation myocardial infarction (STEMI) before primary percutaneous coronary intervention (pPCI) is associated with lower mortality and better clinical outcome. However, there were little data regarding the predictors of IRA patency before pPCI in the setting of STEMI. We aimed to assess the association of platelet to lymphocyte ratio (PLR) with IRA patency in STEMI. A total of 452 patients were enrolled and categorized as occluded or patent IRA. Patency IRA was assessed by the thrombolysis in myocardial infarction (TIMI) flow grade. Blood samples were obtained on admission to calculate PLR. Of all patients, 92 (20.4%) patients revealed pre-pPCI TIMI 3 flow in IRA. The PLR was significantly higher in occluded IRA group (138.4 ± 51.4 vs 95.4 ± 43.5, P < .001). Glucose, troponin I, and neutrophil to lymphocyte ratio (NLR) levels were also higher in occluded IRA group (P < .05). Multivariate regression analysis demonstrated the PLR (odds ratio [OR]: 0.987; 95% confidence interval [CI]: 0.978-0.995, P = .002) and NLR (OR: 0.758; 95% CI: 0.584-0.985, P = .038) on admission as independent predictors of IRA patency. In conclusion, a higher PLR is a powerful and independent predictor of IRA patency in patients with STEMI before pPCI.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>25712290</pmid><doi>10.1177/0003319715573658</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-3197 |
| ispartof | Angiology, 2015-10, Vol.66 (9), p.831-836 |
| issn | 0003-3197 1940-1574 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1710656884 |
| source | MEDLINE; SAGE Complete A-Z List |
| subjects | Aged Biomarkers - blood Blood Platelets Chi-Square Distribution Coronary Angiography Coronary Artery Disease - blood Coronary Artery Disease - complications Coronary Artery Disease - diagnosis Coronary Artery Disease - physiopathology Coronary Circulation Coronary Occlusion - blood Coronary Occlusion - complications Coronary Occlusion - diagnosis Coronary Occlusion - physiopathology Coronary Vessels - diagnostic imaging Coronary Vessels - physiopathology Female Humans Logistic Models Lymphocyte Count Lymphocytes Male Middle Aged Multivariate Analysis Myocardial Infarction - blood Myocardial Infarction - diagnosis Myocardial Infarction - etiology Myocardial Infarction - physiopathology Odds Ratio Platelet Count Predictive Value of Tests Retrospective Studies Risk Factors Turkey Vascular Patency |
| title | Platelet to Lymphocyte Ratio Can be a Predictor of Infarct-Related Artery Patency in Patients With ST-Segment Elevation Myocardial Infarction |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T14%3A57%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Platelet%20to%20Lymphocyte%20Ratio%20Can%20be%20a%20Predictor%20of%20Infarct-Related%20Artery%20Patency%20in%20Patients%20With%20ST-Segment%20Elevation%20Myocardial%20Infarction&rft.jtitle=Angiology&rft.au=Yayla,%20%C3%87a%C4%9Fr%C4%B1&rft.date=2015-10-01&rft.volume=66&rft.issue=9&rft.spage=831&rft.epage=836&rft.pages=831-836&rft.issn=0003-3197&rft.eissn=1940-1574&rft_id=info:doi/10.1177/0003319715573658&rft_dat=%3Cproquest_cross%3E1710656884%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1710656884&rft_id=info:pmid/25712290&rft_sage_id=10.1177_0003319715573658&rfr_iscdi=true |