Evaluation of a novel multiplex RT-qPCR assay for the quantification of leukemia-associated BCR-ABL1 translocation

Although monitoring of BCR-ABL1 translocation has become an established practice in the management of chronic myeloid leukemia (CML), the detection limit of the BCR-ABL1 transcripts needs more standardization. The aim of the present study was to evaluate the clinical performances of a novel assay fo...

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Veröffentlicht in:	International journal of hematology 2015-09, Vol.102 (3), p.335-341
Hauptverfasser:	Kottwitz, D., EL Hadi, H., El Amrani, M., Cabezas, S., Dehbi, H., Nadifi, S., Quessar, A., Colomer, D., Moumen, Abdeladim, Sefrioui, EL Hassan
Format:	Artikel
Sprache:	eng
Schlagworte:	Female Fusion Proteins, bcr-abl - blood Fusion Proteins, bcr-abl - genetics Hematology Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive - blood Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Male Medicine Medicine & Public Health Multiplex Polymerase Chain Reaction - methods Oncology Original Article Philadelphia Chromosome Retrospective Studies Reverse Transcriptase Polymerase Chain Reaction - methods RNA, Messenger - blood RNA, Messenger - genetics Translocation, Genetic
Online-Zugang:	Volltext
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