Effect of gravity on vestibular neural development

The timing, molecular basis, and morphophysiological and behavioral consequences of the interaction between external environment and the internal genetic pool that shapes the nervous system over a lifetime remain important questions in basic neuroscientific research. Space station offers the opportu...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Brain Research Reviews 1998-11, Vol.28 (1), p.44-51
Hauptverfasser: Ross, Muriel D, Tomko, David L
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 51
container_issue 1
container_start_page 44
container_title Brain Research Reviews
container_volume 28
creator Ross, Muriel D
Tomko, David L
description The timing, molecular basis, and morphophysiological and behavioral consequences of the interaction between external environment and the internal genetic pool that shapes the nervous system over a lifetime remain important questions in basic neuroscientific research. Space station offers the opportunity to study this interaction over several life cycles in a variety of organisms. This short review considers past work in altered gravity, particularly on the vestibular system, as the basis for proposing future research on space station, and discusses the equipment necessary to achieve goals. It is stressed that, in keeping with the international investment being made in this research endeavor, both the questions asked and the technologies to be developed should be bold. Advantage must be taken of this unique research environment to expand the frontiers of neuroscience.
doi_str_mv 10.1016/S0165-0173(98)00025-3
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_17099954</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0165017398000253</els_id><sourcerecordid>17099954</sourcerecordid><originalsourceid>FETCH-LOGICAL-c528t-744a56050a422f37f3e69f6ad75d1b8f3d405acf099301a89663b20cfe7a63253</originalsourceid><addsrcrecordid>eNqFkEFP3DAQha0KRBfaf1CkHFBVDmnHdmzHJ4QQ0EorcWh7tmadMTLKJls7WYl_Xy-7giOXmcN7b-bpY-ycw3cOXP_4XYaqgRv5zbaXACBULT-wBW-NqLUU_IgtXi0f2WnOTwDKNq0-YSfWWMWFWTBxGwL5qRpD9ZhwG6fnahyqLeUpruYeUzXQnLCvOtpSP27WNEyf2HHAPtPnwz5jf-9u_9z8rJcP979urpe1V6KdatM0qDQowEaIIE2QpG3Q2BnV8VUbZNeAQh_AWgkcW6u1XAnwgQyW-kqesa_7u5s0_ptLI7eO2VPf40DjnB03JWpVU4xqb_RpzDlRcJsU15ieHQe3Y-VeWLkdCGdb98LKyZI7PzyYV2vqXlMHOEW_OOiYPfYh4eBjfjuuOYBpi-3L3jZgRjdMKTsB0ABvBLeiyFd7mQqrbaTkso80eOpiKuRdN8Z3ev4HfgWMRg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>17099954</pqid></control><display><type>article</type><title>Effect of gravity on vestibular neural development</title><source>MEDLINE</source><source>NASA Technical Reports Server</source><source>Alma/SFX Local Collection</source><creator>Ross, Muriel D ; Tomko, David L</creator><creatorcontrib>Ross, Muriel D ; Tomko, David L</creatorcontrib><description>The timing, molecular basis, and morphophysiological and behavioral consequences of the interaction between external environment and the internal genetic pool that shapes the nervous system over a lifetime remain important questions in basic neuroscientific research. Space station offers the opportunity to study this interaction over several life cycles in a variety of organisms. This short review considers past work in altered gravity, particularly on the vestibular system, as the basis for proposing future research on space station, and discusses the equipment necessary to achieve goals. It is stressed that, in keeping with the international investment being made in this research endeavor, both the questions asked and the technologies to be developed should be bold. Advantage must be taken of this unique research environment to expand the frontiers of neuroscience.</description><identifier>ISSN: 0165-0173</identifier><identifier>EISSN: 1872-6321</identifier><identifier>DOI: 10.1016/S0165-0173(98)00025-3</identifier><identifier>PMID: 9795127</identifier><language>eng</language><publisher>Legacy CDMS: Elsevier B.V</publisher><subject>Aging - physiology ; Altered gravity ; Animals ; Biological and medical sciences ; Critical period ; Development. Senescence. Regeneration. Transplantation ; Fundamental and applied biological sciences. Psychology ; Gravitation ; Life Sciences (General) ; Nervous System - growth &amp; development ; Nervous System Physiological Phenomena ; Synaptogenesis ; Vertebrates: nervous system and sense organs ; Vestibular macula ; Vestibule, Labyrinth - innervation</subject><ispartof>Brain Research Reviews, 1998-11, Vol.28 (1), p.44-51</ispartof><rights>1998</rights><rights>1999 INIST-CNRS</rights><rights>Copyright 1998 Published by Elsevier Science B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c528t-744a56050a422f37f3e69f6ad75d1b8f3d405acf099301a89663b20cfe7a63253</citedby><cites>FETCH-LOGICAL-c528t-744a56050a422f37f3e69f6ad75d1b8f3d405acf099301a89663b20cfe7a63253</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,313,314,776,780,785,786,788,23910,23911,25119,27901,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=1610078$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9795127$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ross, Muriel D</creatorcontrib><creatorcontrib>Tomko, David L</creatorcontrib><title>Effect of gravity on vestibular neural development</title><title>Brain Research Reviews</title><addtitle>Brain Res Brain Res Rev</addtitle><description>The timing, molecular basis, and morphophysiological and behavioral consequences of the interaction between external environment and the internal genetic pool that shapes the nervous system over a lifetime remain important questions in basic neuroscientific research. Space station offers the opportunity to study this interaction over several life cycles in a variety of organisms. This short review considers past work in altered gravity, particularly on the vestibular system, as the basis for proposing future research on space station, and discusses the equipment necessary to achieve goals. It is stressed that, in keeping with the international investment being made in this research endeavor, both the questions asked and the technologies to be developed should be bold. Advantage must be taken of this unique research environment to expand the frontiers of neuroscience.</description><subject>Aging - physiology</subject><subject>Altered gravity</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Critical period</subject><subject>Development. Senescence. Regeneration. Transplantation</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gravitation</subject><subject>Life Sciences (General)</subject><subject>Nervous System - growth &amp; development</subject><subject>Nervous System Physiological Phenomena</subject><subject>Synaptogenesis</subject><subject>Vertebrates: nervous system and sense organs</subject><subject>Vestibular macula</subject><subject>Vestibule, Labyrinth - innervation</subject><issn>0165-0173</issn><issn>1872-6321</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>CYI</sourceid><sourceid>EIF</sourceid><recordid>eNqFkEFP3DAQha0KRBfaf1CkHFBVDmnHdmzHJ4QQ0EorcWh7tmadMTLKJls7WYl_Xy-7giOXmcN7b-bpY-ycw3cOXP_4XYaqgRv5zbaXACBULT-wBW-NqLUU_IgtXi0f2WnOTwDKNq0-YSfWWMWFWTBxGwL5qRpD9ZhwG6fnahyqLeUpruYeUzXQnLCvOtpSP27WNEyf2HHAPtPnwz5jf-9u_9z8rJcP979urpe1V6KdatM0qDQowEaIIE2QpG3Q2BnV8VUbZNeAQh_AWgkcW6u1XAnwgQyW-kqesa_7u5s0_ptLI7eO2VPf40DjnB03JWpVU4xqb_RpzDlRcJsU15ieHQe3Y-VeWLkdCGdb98LKyZI7PzyYV2vqXlMHOEW_OOiYPfYh4eBjfjuuOYBpi-3L3jZgRjdMKTsB0ABvBLeiyFd7mQqrbaTkso80eOpiKuRdN8Z3ev4HfgWMRg</recordid><startdate>19981101</startdate><enddate>19981101</enddate><creator>Ross, Muriel D</creator><creator>Tomko, David L</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>CYE</scope><scope>CYI</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope></search><sort><creationdate>19981101</creationdate><title>Effect of gravity on vestibular neural development</title><author>Ross, Muriel D ; Tomko, David L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c528t-744a56050a422f37f3e69f6ad75d1b8f3d405acf099301a89663b20cfe7a63253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Aging - physiology</topic><topic>Altered gravity</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Critical period</topic><topic>Development. Senescence. Regeneration. Transplantation</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gravitation</topic><topic>Life Sciences (General)</topic><topic>Nervous System - growth &amp; development</topic><topic>Nervous System Physiological Phenomena</topic><topic>Synaptogenesis</topic><topic>Vertebrates: nervous system and sense organs</topic><topic>Vestibular macula</topic><topic>Vestibule, Labyrinth - innervation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ross, Muriel D</creatorcontrib><creatorcontrib>Tomko, David L</creatorcontrib><collection>NASA Scientific and Technical Information</collection><collection>NASA Technical Reports Server</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><jtitle>Brain Research Reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ross, Muriel D</au><au>Tomko, David L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of gravity on vestibular neural development</atitle><jtitle>Brain Research Reviews</jtitle><addtitle>Brain Res Brain Res Rev</addtitle><date>1998-11-01</date><risdate>1998</risdate><volume>28</volume><issue>1</issue><spage>44</spage><epage>51</epage><pages>44-51</pages><issn>0165-0173</issn><eissn>1872-6321</eissn><abstract>The timing, molecular basis, and morphophysiological and behavioral consequences of the interaction between external environment and the internal genetic pool that shapes the nervous system over a lifetime remain important questions in basic neuroscientific research. Space station offers the opportunity to study this interaction over several life cycles in a variety of organisms. This short review considers past work in altered gravity, particularly on the vestibular system, as the basis for proposing future research on space station, and discusses the equipment necessary to achieve goals. It is stressed that, in keeping with the international investment being made in this research endeavor, both the questions asked and the technologies to be developed should be bold. Advantage must be taken of this unique research environment to expand the frontiers of neuroscience.</abstract><cop>Legacy CDMS</cop><pub>Elsevier B.V</pub><pmid>9795127</pmid><doi>10.1016/S0165-0173(98)00025-3</doi><tpages>8</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0165-0173
ispartof Brain Research Reviews, 1998-11, Vol.28 (1), p.44-51
issn 0165-0173
1872-6321
language eng
recordid cdi_proquest_miscellaneous_17099954
source MEDLINE; NASA Technical Reports Server; Alma/SFX Local Collection
subjects Aging - physiology
Altered gravity
Animals
Biological and medical sciences
Critical period
Development. Senescence. Regeneration. Transplantation
Fundamental and applied biological sciences. Psychology
Gravitation
Life Sciences (General)
Nervous System - growth & development
Nervous System Physiological Phenomena
Synaptogenesis
Vertebrates: nervous system and sense organs
Vestibular macula
Vestibule, Labyrinth - innervation
title Effect of gravity on vestibular neural development
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T18%3A02%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20gravity%20on%20vestibular%20neural%20development&rft.jtitle=Brain%20Research%20Reviews&rft.au=Ross,%20Muriel%20D&rft.date=1998-11-01&rft.volume=28&rft.issue=1&rft.spage=44&rft.epage=51&rft.pages=44-51&rft.issn=0165-0173&rft.eissn=1872-6321&rft_id=info:doi/10.1016/S0165-0173(98)00025-3&rft_dat=%3Cproquest_cross%3E17099954%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=17099954&rft_id=info:pmid/9795127&rft_els_id=S0165017398000253&rfr_iscdi=true