Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics

Aldehyde dehydrogenase-2 (ALDH2) eliminates most of the acetaldehyde produced during alcohol metabolism. In some drinkers, a mutant ALDH2 allele contributes to diminished activity of the enzyme, dramatically increasing the risk for esophageal cancer. This study was designed to evaluate the ALDH2 gen...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Carcinogenesis (New York) 1998-08, Vol.19 (8), p.1383-1387
Hauptverfasser:	YOKOYAMA, A, MURAMATSU, T, ISHII, H, OHMORI, T, YOKOYAMA, T, OKUYAMA, K, TAKAHASHI, H, HASEGAWA, Y, HIGUCHI, S, MARUYAMA, K, SHIRAKURA, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alcoholism - enzymology Alcoholism and acute alcohol poisoning Aldehyde Dehydrogenase - genetics Aldehyde Dehydrogenase, Mitochondrial Alleles Biological and medical sciences Colonic Neoplasms - enzymology Colonic Neoplasms - genetics Esophageal Neoplasms - enzymology Esophageal Neoplasms - genetics Genotype Humans Japan Male Medical sciences Middle Aged Neoplasms - enzymology Neoplasms - genetics Oropharyngeal Neoplasms - enzymology Oropharyngeal Neoplasms - genetics Polymorphism, Genetic - genetics Smoking Stomach Neoplasms - enzymology Stomach Neoplasms - genetics Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!