Organic Radical Contrast Agents Based on Polyacetylenes Containing 2,2,6,6-Tetramethylpiperidine 1-Oxyl (TEMPO): Targeted Magnetic Resonance (MR)/Optical Bimodal Imaging of Folate Receptor Expressing HeLa Tumors in Vitro and in Vivo super(a)

Nitroxides have great potential as magnetic resonance imaging (MRI) contrast agents for tumor detection. Polyacetylenes(PAs) containing 2,2,6,6-tetramethyl-piperidine oxyl (TEMPO) and poly(ethylene glycol) were synthesized via metathesis polymerization of the corresponding substituted acetylenes to...

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Veröffentlicht in:	Macromolecular bioscience 2015-06, Vol.15 (6), p.788-798
Hauptverfasser:	Huang, Lixia, Yan, Chenggong, Cui, Danting, Yan, Yichen, Liu, Xiang, Lu, Xinwei, Tan, Xiangliang, Lu, Xiaodan, Xu, Jun, Xu, Yikai, Liu, Ruiyuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Contrast agents Imaging In vitro testing Magnetic resonance imaging Polyacetylenes Radicals Surgical implants Tumors
Online-Zugang:	Volltext
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