Mitochondrial DNA content as a viability score in human euploid embryos: less is better

Objective To investigate the clinical relevance of mitochondrial DNA (mtDNA) content as a viability score in human euploid embryos. Design Retrospective analysis of mtDNA content of transferred euploid embryos. Setting Reproductive genetics laboratory. Patient(s) Single-embryo transfer in 270 patien...

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Veröffentlicht in:	Fertility and sterility 2015-09, Vol.104 (3), p.534-541.e1
Hauptverfasser:	Diez-Juan, Antonio, Ph.D, Rubio, Carmen, Ph.D, Marin, Carlos, B.Sc, Martinez, Sebastian, B.Sc, Al-Asmar, Nasser, M.Sc, Riboldi, Marcia, Ph.D, Díaz-Gimeno, Patricia, Ph.D, Valbuena, Diana, M.D., Ph.D, Simón, Carlos, M.D., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Blastocyst - chemistry Blastocyst - pathology Cell Survival DNA Copy Number Variations DNA, Mitochondrial - analysis Embryo Culture Techniques Embryo Implantation Embryo Transfer Energy Female Fertilization in Vitro - adverse effects Genetic Markers human embryo Humans implantation Internal Medicine Male mitochondrial DNA Obstetrics and Gynecology Ploidies prediction Pregnancy Pregnancy Rate Retrospective Studies Risk Factors Time Factors Treatment Outcome
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