Heat killed multi-serotype Shigella immunogens induced humoral immunity and protection against heterologous challenge in rabbit model

Abstract Recently we have shown the homologous protective efficacy of heat killed multi-serotype Shigella (HKMS) immunogens in a guinea pig colitis model. In our present study, we have advanced our research by immunizing rabbits with a reduced number of oral doses and evaluating the host’s adaptive...

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Veröffentlicht in:	Immunobiology (1979) 2015-11, Vol.220 (11), p.1275-1283
Hauptverfasser:	Nag, Dhrubajyoti, Sinha, Ritam, Mitra, Soma, Barman, Soumik, Takeda, Yoshifumi, Shinoda, Sumio, Chakrabarti, M.K, Koley, Hemanta
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive Immunity Administration, Oral Advanced Basic Science Allergy and Immunology Animals Antibodies, Bacterial - blood Antibodies, Bacterial - immunology Antibody Formation Antigens, Bacterial - administration & dosage Antigens, Bacterial - immunology Disease Models, Animal Dysentery, Bacillary - immunology Dysentery, Bacillary - prevention & control Female Heat killed multi serotype Humoral immunity Immunity, Cellular Immunity, Humoral Immunization Immunoglobulin A, Secretory - blood Immunoglobulin A, Secretory - immunology Immunoglobulin Isotypes - blood Immunoglobulin Isotypes - immunology Male Plasma Cells - immunology Plasma Cells - metabolism Rabbit model Rabbits Serogroup Shigella Shigella - classification Shigella - immunology
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