The Specific Roles of JAK/STAT Signaling Pathway in Sepsis

The Janus kinase-signal transducer and activator of transcription (JAK/STAT) pathway is a principal signaling pathway for the signal transduction of many pivotal cytokines involved in sepsis. Binding of cytokines to corresponding receptors can activate associated JAK kinases, which selectively phosp...

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Veröffentlicht in:	Inflammation 2015-08, Vol.38 (4), p.1599-1608
Hauptverfasser:	Cai, Bin, Cai, Jian-ping, Luo, Yu-long, Chen, Cheng, Zhang, Sen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Humans Immunology Internal Medicine Janus Kinases - physiology Pathology Pharmacology/Toxicology Rheumatology Sepsis - metabolism Sepsis - pathology Signal Transduction - physiology STAT Transcription Factors - physiology
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