The tumor suppressor role of PAQR3 in osteosarcoma

Osteosarcoma is the most common primary bone malignancy; however, the molecular mechanisms of development are not well understood. Progestin and AdipoQ receptors (PAQR3), a protein specifically localized in the Golgi apparatus, was recently characterized as a new tumor suppressor. Little is known ab...

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Veröffentlicht in:	Tumor biology 2015-05, Vol.36 (5), p.3319-3324
Hauptverfasser:	Ma, Zhiqiang, Wang, Yanlong, Piao, Taikui, Li, Zhaopeng, Zhang, Hongyu, Liu, Zhixin, Liu, Jianyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Bone cancer Bone Neoplasms - metabolism Bone Neoplasms - pathology Cancer Research Cell growth Cell Line, Tumor Cell Movement Cell Proliferation Extracellular Signal-Regulated MAP Kinases - metabolism Humans Intracellular Signaling Peptides and Proteins - analysis Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - physiology Membrane Proteins - analysis Membrane Proteins - genetics Membrane Proteins - physiology Neoplasm Invasiveness Osteosarcoma - metabolism Osteosarcoma - pathology Phosphorylation Protein expression Research Article Tumor Suppressor Proteins - physiology Tumorigenesis
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