Association of the leptin receptor Gln223 Arg polymorphism with lipid profile in obese Pakistani subjects

Abstract Objective Leptin receptor gene ( LEPR ) encodes a receptor for leptin hormone expressed in hypothalamus and single nucleotide polymorphisms in LEPR may have a considerable effect on obesity phenotype. The aim of this study was to investigate an extensively studied LEPR polymorphism Gln223 A...

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Veröffentlicht in:	Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2015-09, Vol.31 (9), p.1136-1140
Hauptverfasser:	Shabana, N.A., M.Phil, Hasnain, Shahida, Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Asian Continental Ancestry Group - genetics Blood Glucose - metabolism Blood Pressure Body Mass Index Cholesterol Cholesterol - blood Cholesterol, HDL - blood Cholesterol, LDL - blood Female Gastroenterology and Hepatology Genotype Genotypes Humans Insulin Insulin - blood Leptin Leptin - blood Leptin receptor Lipid Metabolism - genetics Lipid parameters Low density lipoprotein Male Middle Aged Obesity Obesity - blood Obesity - genetics Pakistan Polymorphism, Restriction Fragment Length Polymorphism, Single Nucleotide Receptors, Leptin - genetics Rodents Single nucleotide polymorphism Triglycerides - blood
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