Impact of blood glucose, diabetes, insulin, and obesity on standardized uptake values in tumors and healthy organs on 18F-FDG PET/CT

Chronically altered glucose metabolism interferes with 18F-FDG uptake in malignant tissue and healthy organs and may therefore lower tumor detection in 18F-FDG PET/CT. The present study assesses the impact of elevated blood glucose levels (BGL), diabetes, insulin treatment, and obesity on 18F-FDG up...

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Veröffentlicht in:	Nuclear medicine and biology 2013-02, Vol.40 (2), p.206-213
Hauptverfasser:	Büsing, Karen A., Schönberg, Stefan O., Brade, Joachim, Wasser, Klaus
Format:	Artikel
Sprache:	eng
Schlagworte:	18F-FDG PET/CT Biodistribution Biological Transport - drug effects Blood Glucose - metabolism Diabetes Diabetes Complications - diagnostic imaging Diabetes Complications - drug therapy Diabetes Complications - metabolism Diabetes Complications - physiopathology Female Fluorodeoxyglucose F18 - metabolism Humans Hyperglycemia Insulin Insulin - pharmacology Kidney - physiopathology Liver - physiopathology Male Middle Aged Multimodal Imaging Neoplasms - diagnostic imaging Neoplasms - drug therapy Neoplasms - metabolism Neoplasms - physiopathology Obesity Obesity - complications Positron-Emission Tomography Reference Standards Retrospective Studies Tomography, X-Ray Computed
Online-Zugang:	Volltext
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