Neurosyphilis in psychiatric practice: a case-based discussion of clinical evaluation and diagnosis
Abstract Objective Neurosyphilis can present with a wide range of neuropsychiatric symptoms. Hence, psychiatrists need to be familiar with tests for syphilis screening and how to interpret syphilis serologic tests. Methods We present four cases of patients with positive syphilis tests encountered in...
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Veröffentlicht in: | General hospital psychiatry 2015-09, Vol.37 (5), p.459-463 |
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container_title | General hospital psychiatry |
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creator | Gatchel, Jennifer, M.D., Ph.D Legesse, Benalfew, M.D Tayeb, Safwan, M.D Murray, Evan, M.D Price, Bruce, M.D |
description | Abstract Objective Neurosyphilis can present with a wide range of neuropsychiatric symptoms. Hence, psychiatrists need to be familiar with tests for syphilis screening and how to interpret syphilis serologic tests. Methods We present four cases of patients with positive syphilis tests encountered in a psychiatric hospital. Results Two cases were treated for neurosyphilis, while the other two cases did not have active syphilis infection despite positive results. Conclusion We thus highlight the challenges encountered by psychiatrists in screening for and diagnosing cases of neurosyphilis. |
doi_str_mv | 10.1016/j.genhosppsych.2015.04.012 |
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Hence, psychiatrists need to be familiar with tests for syphilis screening and how to interpret syphilis serologic tests. Methods We present four cases of patients with positive syphilis tests encountered in a psychiatric hospital. Results Two cases were treated for neurosyphilis, while the other two cases did not have active syphilis infection despite positive results. Conclusion We thus highlight the challenges encountered by psychiatrists in screening for and diagnosing cases of neurosyphilis.</description><identifier>ISSN: 0163-8343</identifier><identifier>EISSN: 1873-7714</identifier><identifier>DOI: 10.1016/j.genhosppsych.2015.04.012</identifier><identifier>PMID: 26022384</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Aged, 80 and over ; Algorithms ; Diagnosis, Differential ; Female ; Humans ; Male ; Middle Aged ; Neurosyphilis ; Neurosyphilis - diagnosis ; Psychiatry ; Psychotic disorder ; RPR ; Syphilis - diagnosis ; Syphilis Serodiagnosis ; Tabes dorsalis</subject><ispartof>General hospital psychiatry, 2015-09, Vol.37 (5), p.459-463</ispartof><rights>Elsevier Inc.</rights><rights>2015 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c505t-2dde00f1f5ee2567a7d387c8b67efa578990a1837930d8d33670bee485a3d853</citedby><cites>FETCH-LOGICAL-c505t-2dde00f1f5ee2567a7d387c8b67efa578990a1837930d8d33670bee485a3d853</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.genhosppsych.2015.04.012$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26022384$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gatchel, Jennifer, M.D., Ph.D</creatorcontrib><creatorcontrib>Legesse, Benalfew, M.D</creatorcontrib><creatorcontrib>Tayeb, Safwan, M.D</creatorcontrib><creatorcontrib>Murray, Evan, M.D</creatorcontrib><creatorcontrib>Price, Bruce, M.D</creatorcontrib><title>Neurosyphilis in psychiatric practice: a case-based discussion of clinical evaluation and diagnosis</title><title>General hospital psychiatry</title><addtitle>Gen Hosp Psychiatry</addtitle><description>Abstract Objective Neurosyphilis can present with a wide range of neuropsychiatric symptoms. Hence, psychiatrists need to be familiar with tests for syphilis screening and how to interpret syphilis serologic tests. Methods We present four cases of patients with positive syphilis tests encountered in a psychiatric hospital. Results Two cases were treated for neurosyphilis, while the other two cases did not have active syphilis infection despite positive results. Conclusion We thus highlight the challenges encountered by psychiatrists in screening for and diagnosing cases of neurosyphilis.</description><subject>Adult</subject><subject>Aged, 80 and over</subject><subject>Algorithms</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neurosyphilis</subject><subject>Neurosyphilis - diagnosis</subject><subject>Psychiatry</subject><subject>Psychotic disorder</subject><subject>RPR</subject><subject>Syphilis - diagnosis</subject><subject>Syphilis Serodiagnosis</subject><subject>Tabes dorsalis</subject><issn>0163-8343</issn><issn>1873-7714</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkcFu1DAQhi0EotvCK6CIE5eEsR3HTg9IqEBBquBA75bXnnS9ZJPgSSrt2-OwLUKcuNiS9c0_nm8Ye82h4sCbt_vqDofdSNNER7-rBHBVQV0BF0_YhhstS615_ZRtMixLI2t5xs6J9gCghJLP2ZloQAhp6g3zX3FJIx2nXewjFXEofodGN6foiyk5P0ePl4UrvCMst_kIRYjkF6I4DsXYFb6PQ_SuL_De9Yub12c3rJS7G0aK9II961xP-PLhvmC3nz7eXn0ub75df7l6f1N6BWouRQgI0PFOIQrVaKeDNNqbbaOxc0qbtgXHjdSthGCClI2GLWJtlJPBKHnB3pxipzT-XJBme8j_xL53A44LWa7BtCBq0WT08oT6PDsl7OyU4sGlo-VgV8d2b_92bFfHFmqbHefiVw99lu0Bw5_SR6kZ-HACMA97HzFZ8hEHjyEm9LMNY_y_Pu_-iXk0_QOPSPtxSUPWabklYcF-X7e9LpurvOi21fIXarCq0Q</recordid><startdate>20150901</startdate><enddate>20150901</enddate><creator>Gatchel, Jennifer, M.D., Ph.D</creator><creator>Legesse, Benalfew, M.D</creator><creator>Tayeb, Safwan, M.D</creator><creator>Murray, Evan, M.D</creator><creator>Price, Bruce, M.D</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150901</creationdate><title>Neurosyphilis in psychiatric practice: a case-based discussion of clinical evaluation and diagnosis</title><author>Gatchel, Jennifer, M.D., Ph.D ; Legesse, Benalfew, M.D ; Tayeb, Safwan, M.D ; Murray, Evan, M.D ; Price, Bruce, M.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c505t-2dde00f1f5ee2567a7d387c8b67efa578990a1837930d8d33670bee485a3d853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged, 80 and over</topic><topic>Algorithms</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neurosyphilis</topic><topic>Neurosyphilis - diagnosis</topic><topic>Psychiatry</topic><topic>Psychotic disorder</topic><topic>RPR</topic><topic>Syphilis - diagnosis</topic><topic>Syphilis Serodiagnosis</topic><topic>Tabes dorsalis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gatchel, Jennifer, M.D., Ph.D</creatorcontrib><creatorcontrib>Legesse, Benalfew, M.D</creatorcontrib><creatorcontrib>Tayeb, Safwan, M.D</creatorcontrib><creatorcontrib>Murray, Evan, M.D</creatorcontrib><creatorcontrib>Price, Bruce, M.D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>General hospital psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gatchel, Jennifer, M.D., Ph.D</au><au>Legesse, Benalfew, M.D</au><au>Tayeb, Safwan, M.D</au><au>Murray, Evan, M.D</au><au>Price, Bruce, M.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neurosyphilis in psychiatric practice: a case-based discussion of clinical evaluation and diagnosis</atitle><jtitle>General hospital psychiatry</jtitle><addtitle>Gen Hosp Psychiatry</addtitle><date>2015-09-01</date><risdate>2015</risdate><volume>37</volume><issue>5</issue><spage>459</spage><epage>463</epage><pages>459-463</pages><issn>0163-8343</issn><eissn>1873-7714</eissn><abstract>Abstract Objective Neurosyphilis can present with a wide range of neuropsychiatric symptoms. Hence, psychiatrists need to be familiar with tests for syphilis screening and how to interpret syphilis serologic tests. Methods We present four cases of patients with positive syphilis tests encountered in a psychiatric hospital. Results Two cases were treated for neurosyphilis, while the other two cases did not have active syphilis infection despite positive results. Conclusion We thus highlight the challenges encountered by psychiatrists in screening for and diagnosing cases of neurosyphilis.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26022384</pmid><doi>10.1016/j.genhosppsych.2015.04.012</doi><tpages>5</tpages></addata></record> |
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subjects | Adult Aged, 80 and over Algorithms Diagnosis, Differential Female Humans Male Middle Aged Neurosyphilis Neurosyphilis - diagnosis Psychiatry Psychotic disorder RPR Syphilis - diagnosis Syphilis Serodiagnosis Tabes dorsalis |
title | Neurosyphilis in psychiatric practice: a case-based discussion of clinical evaluation and diagnosis |
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