Preparation and characterisation of hexamidine salts

[Display omitted] Hexamidine diisethionate (HEX D) has been used in the personal care industry and in a number of over-the-counter (OTC) drug products as an antimicrobial agent since the 1950’s. Recently, the compound has also been investigated for its beneficial effects on skin health. Surprisingly...

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Veröffentlicht in:	International journal of pharmaceutics 2015-09, Vol.493 (1-2), p.404-411
Hauptverfasser:	Parisi, Nicola, Matts, Paul J., Lever, Rebecca, Hadgraft, Jonathan, Lane, Majella E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - chemistry Benzamidines - chemistry Characterisation Delivery Drug Compounding Drug Stability Hexamidine Hydrogen-Ion Concentration Molecular Weight Pre-formulation Preparation Salts Salts - chemistry Solubility Transition Temperature
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