The Safety and Efficacy of Cryolipolysis: A Systematic Review of Available Literature
Background In the past decade, the practice of body contouring using cryolipolysis has increased tremendously. While numerous anecdotal reports extol the efficacy of this product, the majority of these studies are small, retrospective case-series that lack control groups. Objective The authors aim t...
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| Veröffentlicht in: | Aesthetic surgery journal 2015-09, Vol.35 (7), p.830-836 |
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| creator | Derrick, Chase D. Shridharani, Sachin M. Broyles, Justin M. |
| description | Background
In the past decade, the practice of body contouring using cryolipolysis has increased tremendously. While numerous anecdotal reports extol the efficacy of this product, the majority of these studies are small, retrospective case-series that lack control groups.
Objective
The authors aim to systematically review available literature to better illustrate the efficacy and safety of this new procedure.
Methods
A systematic literature review performed using MEDLINE, Embase, PubMed, and Cochrane databases identified all published studies evaluating cryolipolysis for body contouring.
Results
A total of 34 articles up to February 2015 were identified. Nineteen articles matched the selection criteria and were included in the analysis. Sixteen were evaluated in the final analysis. A total of 1445 patients had reportable data for analysis of the safety profile. Twelve patients (0.82%) reported complications with the most common being diminished sensation lasting greater than 4 weeks. An aggregate total of 295 patients had objective data for evaluation of tissue reduction. The mean time from procedure to objective outcome evaluation was 3.83 months. The mean reduction of subcutaneous tissue was 19.55% with respect to a designated control site.
Conclusions
Selective cryolipolysis appears, at short-term follow-up, to reliably decrease subcutaneous tissue deposits. Reported complications are uncommon and appear to resolve without intervention. Future studies should aim to optimize patient selection and treatment characteristics while obtaining long-term follow-up data.
Level of Evidence
4
Therapeutic |
| doi_str_mv | 10.1093/asj/sjv039 |
| format | Article |
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In the past decade, the practice of body contouring using cryolipolysis has increased tremendously. While numerous anecdotal reports extol the efficacy of this product, the majority of these studies are small, retrospective case-series that lack control groups.
Objective
The authors aim to systematically review available literature to better illustrate the efficacy and safety of this new procedure.
Methods
A systematic literature review performed using MEDLINE, Embase, PubMed, and Cochrane databases identified all published studies evaluating cryolipolysis for body contouring.
Results
A total of 34 articles up to February 2015 were identified. Nineteen articles matched the selection criteria and were included in the analysis. Sixteen were evaluated in the final analysis. A total of 1445 patients had reportable data for analysis of the safety profile. Twelve patients (0.82%) reported complications with the most common being diminished sensation lasting greater than 4 weeks. An aggregate total of 295 patients had objective data for evaluation of tissue reduction. The mean time from procedure to objective outcome evaluation was 3.83 months. The mean reduction of subcutaneous tissue was 19.55% with respect to a designated control site.
Conclusions
Selective cryolipolysis appears, at short-term follow-up, to reliably decrease subcutaneous tissue deposits. Reported complications are uncommon and appear to resolve without intervention. Future studies should aim to optimize patient selection and treatment characteristics while obtaining long-term follow-up data.
Level of Evidence
4
Therapeutic</description><identifier>ISSN: 1090-820X</identifier><identifier>EISSN: 1527-330X</identifier><identifier>DOI: 10.1093/asj/sjv039</identifier><identifier>PMID: 26038367</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Adolescent ; Adult ; Aged ; Cosmetic Techniques ; Cryotherapy - adverse effects ; Cryotherapy - methods ; Female ; Humans ; Lipectomy - adverse effects ; Lipectomy - methods ; Male ; Middle Aged ; Subcutaneous Fat ; Young Adult</subject><ispartof>Aesthetic surgery journal, 2015-09, Vol.35 (7), p.830-836</ispartof><rights>2015 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com 2015</rights><rights>2015 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c419t-636dfab8bb47058b630ff0f4acb3fae3501e587bb296cd4961068ac2058e7d63</citedby><cites>FETCH-LOGICAL-c419t-636dfab8bb47058b630ff0f4acb3fae3501e587bb296cd4961068ac2058e7d63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1578,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26038367$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Derrick, Chase D.</creatorcontrib><creatorcontrib>Shridharani, Sachin M.</creatorcontrib><creatorcontrib>Broyles, Justin M.</creatorcontrib><title>The Safety and Efficacy of Cryolipolysis: A Systematic Review of Available Literature</title><title>Aesthetic surgery journal</title><addtitle>Aesthet Surg J</addtitle><description>Background
In the past decade, the practice of body contouring using cryolipolysis has increased tremendously. While numerous anecdotal reports extol the efficacy of this product, the majority of these studies are small, retrospective case-series that lack control groups.
Objective
The authors aim to systematically review available literature to better illustrate the efficacy and safety of this new procedure.
Methods
A systematic literature review performed using MEDLINE, Embase, PubMed, and Cochrane databases identified all published studies evaluating cryolipolysis for body contouring.
Results
A total of 34 articles up to February 2015 were identified. Nineteen articles matched the selection criteria and were included in the analysis. Sixteen were evaluated in the final analysis. A total of 1445 patients had reportable data for analysis of the safety profile. Twelve patients (0.82%) reported complications with the most common being diminished sensation lasting greater than 4 weeks. An aggregate total of 295 patients had objective data for evaluation of tissue reduction. The mean time from procedure to objective outcome evaluation was 3.83 months. The mean reduction of subcutaneous tissue was 19.55% with respect to a designated control site.
Conclusions
Selective cryolipolysis appears, at short-term follow-up, to reliably decrease subcutaneous tissue deposits. Reported complications are uncommon and appear to resolve without intervention. Future studies should aim to optimize patient selection and treatment characteristics while obtaining long-term follow-up data.
Level of Evidence
4
Therapeutic</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Cosmetic Techniques</subject><subject>Cryotherapy - adverse effects</subject><subject>Cryotherapy - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Lipectomy - adverse effects</subject><subject>Lipectomy - methods</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Subcutaneous Fat</subject><subject>Young Adult</subject><issn>1090-820X</issn><issn>1527-330X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90E9LwzAYx_EgipvTiy9AchFEqHvatGnqbYz5BwaCm7BbSdInmNGutWknffd2dHr09DyHD7_Dl5BrHx58SNhUuu3UbffAkhMy9qMg9hiDzWn_QwKeCGAzIhfObQF6zcNzMgo4MMF4PCYf60-kK2mw6ajcZXRhjNVSd7Q0dF53ZW6rMu-cdY90Rleda7CQjdX0HfcWvw9qtpc2lypHurQN1rJpa7wkZ0bmDq-Od0LWT4v1_MVbvj2_zmdLT4d-0nic8cxIJZQKY4iE4gyMARNKrZiRyCLwMRKxUkHCdRYm3AcupA56i3HG2YTcDbNVXX616Jq0sE5jnssdlq1L_RiESLgA1tP7geq6dK5Gk1a1LWTdpT6kh4ppXzEdKvb45rjbqgKzP_qbrQe3Ayjb6r-hHxQhe0c</recordid><startdate>20150901</startdate><enddate>20150901</enddate><creator>Derrick, Chase D.</creator><creator>Shridharani, Sachin M.</creator><creator>Broyles, Justin M.</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150901</creationdate><title>The Safety and Efficacy of Cryolipolysis: A Systematic Review of Available Literature</title><author>Derrick, Chase D. ; Shridharani, Sachin M. ; Broyles, Justin M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c419t-636dfab8bb47058b630ff0f4acb3fae3501e587bb296cd4961068ac2058e7d63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Cosmetic Techniques</topic><topic>Cryotherapy - adverse effects</topic><topic>Cryotherapy - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Lipectomy - adverse effects</topic><topic>Lipectomy - methods</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Subcutaneous Fat</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Derrick, Chase D.</creatorcontrib><creatorcontrib>Shridharani, Sachin M.</creatorcontrib><creatorcontrib>Broyles, Justin M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Aesthetic surgery journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Derrick, Chase D.</au><au>Shridharani, Sachin M.</au><au>Broyles, Justin M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Safety and Efficacy of Cryolipolysis: A Systematic Review of Available Literature</atitle><jtitle>Aesthetic surgery journal</jtitle><addtitle>Aesthet Surg J</addtitle><date>2015-09-01</date><risdate>2015</risdate><volume>35</volume><issue>7</issue><spage>830</spage><epage>836</epage><pages>830-836</pages><issn>1090-820X</issn><eissn>1527-330X</eissn><abstract>Background
In the past decade, the practice of body contouring using cryolipolysis has increased tremendously. While numerous anecdotal reports extol the efficacy of this product, the majority of these studies are small, retrospective case-series that lack control groups.
Objective
The authors aim to systematically review available literature to better illustrate the efficacy and safety of this new procedure.
Methods
A systematic literature review performed using MEDLINE, Embase, PubMed, and Cochrane databases identified all published studies evaluating cryolipolysis for body contouring.
Results
A total of 34 articles up to February 2015 were identified. Nineteen articles matched the selection criteria and were included in the analysis. Sixteen were evaluated in the final analysis. A total of 1445 patients had reportable data for analysis of the safety profile. Twelve patients (0.82%) reported complications with the most common being diminished sensation lasting greater than 4 weeks. An aggregate total of 295 patients had objective data for evaluation of tissue reduction. The mean time from procedure to objective outcome evaluation was 3.83 months. The mean reduction of subcutaneous tissue was 19.55% with respect to a designated control site.
Conclusions
Selective cryolipolysis appears, at short-term follow-up, to reliably decrease subcutaneous tissue deposits. Reported complications are uncommon and appear to resolve without intervention. Future studies should aim to optimize patient selection and treatment characteristics while obtaining long-term follow-up data.
Level of Evidence
4
Therapeutic</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>26038367</pmid><doi>10.1093/asj/sjv039</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | Aesthetic surgery journal, 2015-09, Vol.35 (7), p.830-836 |
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| language | eng |
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| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged Cosmetic Techniques Cryotherapy - adverse effects Cryotherapy - methods Female Humans Lipectomy - adverse effects Lipectomy - methods Male Middle Aged Subcutaneous Fat Young Adult |
| title | The Safety and Efficacy of Cryolipolysis: A Systematic Review of Available Literature |
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