Gene expression in WAT from healthy humans and monkeys correlates with FGF21‐induced browning of WAT in mice

Objective Identify a gene expression signature in white adipose tissue (WAT) that reports on WAT browning and is associated with a healthy phenotype. Methods RNA from several different adipose depots across three species were analyzed by whole transcriptome profiling, including 1) mouse subcutaneous...

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Veröffentlicht in:	Obesity (Silver Spring, Md.) Md.), 2015-09, Vol.23 (9), p.1818-1829
Hauptverfasser:	Schlessinger, Karni, Li, Wenyu, Tan, Yejun, Liu, Franklin, Souza, Sandra C., Tozzo, Effie, Liu, Kevin, Thompson, John R., Wang, Liangsu, Muise, Eric S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Adipocytes Adipose Tissue, Brown - metabolism Adipose Tissue, White - metabolism Animals Body fat Datasets Female Fibroblast Growth Factors - metabolism Gastrointestinal surgery Gene expression Gene Expression Profiling Haplorhini Humans Hyperglycemia Inflammation Insulin Lipids Metabolic disorders Mice MicroRNAs - genetics Obesity Obesity - metabolism Studies Subcutaneous Fat - metabolism Transcriptome
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