Azole-resistant Aspergillus fumigatus isolates carrying TR34/L98H mutations in Taiwan

Summary Cumulative evidence described the emergence and geographical expansion of azole‐resistant A. fumigatus associated with azole treatment failure. To investigate the status of azole resistance in A. fumigatus in Taiwan, we studied 38 A. fumigatus clinical isolates cultivated from 31 patients at...

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Veröffentlicht in:	Mycoses 2015-09, Vol.58 (9), p.544-549
Hauptverfasser:	Wu, Chi-Jung, Wang, Hsuan-Chen, Lee, Jen-Chieh, Lo, Hsiu-Jung, Dai, Ching-Tzu, Chou, Pei-Hsin, Ko, Wen-Chien, Chen, Yee-Chun
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal Agents - pharmacology Aspergillus fumigatus Aspergillus fumigatus - drug effects Aspergillus fumigatus - genetics Aspergillus fumigatus - isolation & purification azole fungicide Azole resistance Azoles Cytochrome P-450 Enzyme System - genetics Drug Resistance, Multiple, Fungal - genetics Fungal Proteins - genetics Genetic Variation Genotype Humans Microbial Sensitivity Tests Molecular Sequence Data Mutation Mutation, Missense Phylogeny Pulmonary Aspergillosis - epidemiology Pulmonary Aspergillosis - microbiology Retrospective Studies Taiwan Taiwan - epidemiology Time Factors TR34/L98H
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