Toll-like receptor signaling in hematopoietic homeostasis and the pathogenesis of hematologic diseases

Toll-like receptors (TLRs), which are found in innate immune cells, are essential mediators of rapid inflammatory responses and appropriate T-cell activation in response to infection and tissue damage. Accumulating evidence suggests that TLR signaling is involved in normal hematopoiesis and specific...

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Veröffentlicht in:Frontiers of medicine 2015-09, Vol.9 (3), p.288-303
Hauptverfasser: Cannova, Joseph, S.J., Peter Breslin, Zhang, Jiwang
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Sprache:eng
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