Flemingin-Type Prenylated Chalcones from the Sarawak Rainforest Plant Desmodium congestum

In an ongoing program to identify new anti-infective leads, an extract derived from whole plant material of Desmodium congestum collected in the Sarawak rainforest was found to have anti-MRSA activity. Bioassay-guided isolation led to the isolation of two new prenylated chalcones, 5′-O-methyl-3-hydr...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2015-08, Vol.78 (8), p.2141-2144
Hauptverfasser:	Rees, Karlee A, Bermudez, Cindy, Edwards, David J, Elliott, Alysha G, Ripen, Jovita E, Seta, Cynthia, Huang, Johnny X, Cooper, Matthew A, Fraser, James A, Yeo, Tiong Chia, Butler, Mark S
Format:	Artikel
Sprache:	eng
Schlagworte:	Chalcones - chemistry Chalcones - isolation & purification Chalcones - pharmacology Fabaceae - chemistry Gram-Positive Bacteria - drug effects HEK293 Cells Humans Malaysia Methicillin-Resistant Staphylococcus aureus - drug effects Microbial Sensitivity Tests Molecular Structure Nuclear Magnetic Resonance, Biomolecular Prenylation Rainforest
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