The effect of IL-1α on the expression of matrix metalloproteinases, plasminogen activators, and their inhibitors in osteoblastic ROS 17/2.8 cells

Interleukin-1 (IL-1) plays key roles in altering bone matrix turnover. This turnover is regulated by matrix metalloproteinases (MMPs), tissue inhibitor of matrix metalloproteinases (TIMPs), and the plasminogen activation system, including tissue-type plasminogen activator (tPA), urokinase-type plasm...

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Veröffentlicht in:Life sciences (1973) 2006-03, Vol.78 (17), p.1975-1982
Hauptverfasser: Fujisaki, Kyosuke, Tanabe, Natsuko, Suzuki, Naoto, Mitsui, Narihiro, Oka, Hitoshi, Ito, Koichi, Maeno, Masao
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Sprache:eng
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