Suramin prevents fulminant hepatic failure resulting in reduction of lethality through the suppression of NF-[kappa]B activity

Aim Suramin is a symmetrical polysulfonated naphthylamine derivative of urea. There have been few studies on the effect of suramin on cytokines. We examined the effects of suramin on production of inflammatory cytokines. Methods We made an acute liver injury model treated with d-galactosamine (GalN)...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2006-01, Vol.33 (1), p.28-35
Hauptverfasser:	Goto, Takashi, Takeuchi, Satoko, Miura, Kouichi, Ohshima, Shigetoshi, Mikami, Ken-Ichiro, Yoneyama, Kazuo, Sato, Michiko, Shibuya, Tomomi, Watanabe, Daisuke, Kataoka, Ei, Segawa, Daisuke, Endo, Ayako, Sato, Wataru, Yoshino, Ryutaro, Watanabe, Sumio
Format:	Artikel
Sprache:	eng
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