Epithelial Ovarian Cancer Metastatic to the Central Nervous System and a Family History Concerning for Hereditary Breast and Ovarian Cancer—A Potential Relationship

OBJECTIVESTo estimate the frequency of hereditary breast and ovarian cancer (HBOC) in women with central nervous system (CNS) metastasis from epithelial ovarian cancer (EOC) and to evaluate for a potential relationship between HBOC status and survival. METHODS AND MATERIALSA total of 1240 cases of E...

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Veröffentlicht in:	International journal of gynecological cancer 2015-09, Vol.25 (7), p.1232-1238
Hauptverfasser:	Jernigan, Amelia M, Mahdi, Haider, Rose, Peter G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Clear Cell - genetics Adenocarcinoma, Clear Cell - mortality Adenocarcinoma, Clear Cell - pathology Adenocarcinoma, Clear Cell - therapy Adenocarcinoma, Mucinous - genetics Adenocarcinoma, Mucinous - mortality Adenocarcinoma, Mucinous - pathology Adenocarcinoma, Mucinous - therapy Adult Aged Brain Neoplasms - genetics Brain Neoplasms - mortality Brain Neoplasms - secondary Brain Neoplasms - therapy Breast cancer Cystadenocarcinoma, Serous - genetics Cystadenocarcinoma, Serous - mortality Cystadenocarcinoma, Serous - pathology Cystadenocarcinoma, Serous - therapy Endometrial Neoplasms - genetics Endometrial Neoplasms - mortality Endometrial Neoplasms - pathology Endometrial Neoplasms - therapy Family medical history Female Follow-Up Studies Genetic disorders Genetic Predisposition to Disease Genetic Testing Humans Lymphatic Metastasis Metastasis Middle Aged Mutation Mutation - genetics Neoplasm Invasiveness Neoplasm Staging Nervous system Ovarian cancer Ovarian Neoplasms - genetics Ovarian Neoplasms - mortality Ovarian Neoplasms - pathology Ovarian Neoplasms - therapy Prognosis Spinal Cord Neoplasms - genetics Spinal Cord Neoplasms - mortality Spinal Cord Neoplasms - secondary Spinal Cord Neoplasms - therapy Survival Rate Womens health
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