Hepatic Metabolism of Methyl Anthranilate and Methyl N-Methylanthranilate as Food Flavoring Agents in Relation to Allergenicity in the Guinea Pig

To assess the safety of the food flavoring agents, methyl anthranilate (MA) and methyl N-methylanthranilate (MNMA), their relationships with metabolism and allergenicity were examined in guinea pigs. Both MA and MNMA were hydrolyzed to anthranilic acid (AA) and N-methylanthranilic acid (N-methylAA),...

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Veröffentlicht in:	Journal of Health Science 2005, Vol.51(6), pp.667-675
Hauptverfasser:	Yamaori, Satoshi, Yokozuka, Hisayo, Sasama, Aya, Funahashi, Tatsuya, Kimura, Toshiyuki, Yamamoto, Ikuo, Watanabe, Kazuhito
Format:	Artikel
Sprache:	eng
Schlagworte:	anthranilic acid carboxylesterase cytochrome P450 methyl anthranilate methyl N-methylanthranilate skin reaction
Online-Zugang:	Volltext
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