Relationship Between Sunlight Exposure and a Key Genetic Alteration in Basal Cell Carcinoma

Background: Basal cell carcinoma (BCC) of the skin is the most common cancer in humans. Epidemiologic studies implicate sunlight exposure as one risk factor, but the limited association between BCCs and UVB radiation (i.e., UV radiation of a wavelength of 280–320 nm) suggests that additional factors...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1996-03, Vol.88 (6), p.349-354
Hauptverfasser:	Gailani, Mae R., Leffell, David J., Ziegler, AnneMarie, Gross, Earl G., Brash, Douglas E., Bale, Allen E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Alleles Biological and medical sciences Carcinoma, Basal Cell - etiology Carcinoma, Basal Cell - genetics Child Chromosomes, Human, Pair 9 - radiation effects Dermatology Female Gene Deletion Genes Genes, p53 Heterozygote Humans Male Medical sciences Middle Aged Mutation Neoplasms, Radiation-Induced - etiology Neoplasms, Radiation-Induced - genetics Skin cancer Skin Neoplasms - etiology Skin Neoplasms - genetics Sunlight - adverse effects Tumors of the skin and soft tissue. Premalignant lesions Ultraviolet radiation Ultraviolet Rays - adverse effects
Online-Zugang:	Volltext
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