Post-translational Modification of Human Brain Type I Inositol-1,4,5-trisphosphate 5-Phosphatase by Farnesylation

In brain, type I inositol-1,4,5-trisphosphate 5-phosphatase (InsP 5-phosphatase) is the major isoenzyme hydrolyzing the calcium-mobilizing second messenger InsP . Activity of this enzyme could be measured in both soluble and particulate fractions of tissue homogenates. The protein sequence showed a...

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Veröffentlicht in:	The Journal of biological chemistry 1996-04, Vol.271 (17), p.10419-10424
Hauptverfasser:	De Smedt, F, Boom, A, Pesesse, X, Schiffmann, S N, Erneux, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Brain - enzymology Cell Line Chlorocebus aethiops CHO Cells Cricetinae DNA Primers - chemistry Fluorescent Antibody Technique, Indirect Humans Inositol Polyphosphate 5-Phosphatases Molecular Sequence Data Mutagenesis, Site-Directed Phosphoric Monoester Hydrolases - metabolism Protein Prenylation Purkinje Cells - enzymology Rats Recombinant Proteins
Online-Zugang:	Volltext
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