A Controlled Trial of Zidovudine in Primary Human Immunodeficiency Virus Infection

Controlled trials have shown that treatment with zidovudine (Retrovir) late in the course of infection with the human immunodeficiency virus (HIV) type 1 results in decreased rates of disease progression and death, 1 , 2 but there is no consensus on the benefit of antiretroviral treatment in asympto...

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Veröffentlicht in:	The New England journal of medicine 1995-08, Vol.333 (7), p.408-413
Hauptverfasser:	Kinloch-de Loës, Sabine, Hirschel, Bernard J, Hoen, Bruno, Cooper, David A, Tindall, Brett, Carr, Andrew, Saurat, Jean-Hilaire, Clumeck, Nathan, Lazzarin, Adriano, Mathiesen, Lars, Raffi, François, Antunes, Francisco, von Overbeck, Jan, Lüthy, Ruedi, Glauser, Michel, Hawkins, David, Baumberger, Christophe, Yerly, Sabine, Perneger, Thomas V, Perrin, Luc
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult AIDS AIDS-Related Opportunistic Infections - epidemiology AIDS-Related Opportunistic Infections - prevention & control Antibiotics. Antiinfectious agents. Antiparasitic agents Antigens Antiretroviral drugs Antiretroviral therapy Antiviral agents Biological and medical sciences Candidiasis CD4 antigen CD4 Lymphocyte Count - drug effects Clinical trials Disease Progression Disease-Free Survival Double-Blind Method Drug therapy Enrollments Female Follow-Up Studies Herpes zoster HIV HIV Infections - drug therapy HIV Infections - immunology HIV Infections - virology HIV-1 - genetics HIV-1 - isolation & purification Hospitals Human immunodeficiency virus Humans Immune response Infections Infectious diseases Laboratories Leukokeratosis Lymphocytes Male Medical sciences Medicine Middle Aged Opportunist infection Oral hairy leukoplakia Pharmacology. Drug treatments RNA, Viral - analysis Time Factors Trends Virology Zidovudine Zidovudine - administration & dosage Zidovudine - adverse effects Zidovudine - therapeutic use
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