Paroxetine is effective in desensitizing 5-HT sub(1A) receptor function in adult offspring exposed prenatally to cocaine

Rationale: Desensitization of postsynaptic 5-HT sub(1A) receptors may be responsible for the therapeutic effectiveness of serotonin selective uptake inhibitors (SSRIs). As prenatal cocaine exposure produces long-term deficits in 5-HT neurons in offspring, it may alter the ability of postsynaptic 5-H...

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Veröffentlicht in:	Psychopharmacology 2005-07, Vol.180 (2), p.316-326
Hauptverfasser:	Chen, Zhuo, Tetzlaff, Julie, Sripathirathan, Kumar, Carrasco, Gonzalo A, Shankaran, Mahalakshmi, Kar, Louis D, Muma, Nancy A, Battaglia, George
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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