Impact of TGF-β1 -509C/T and 869T/C polymorphisms on glioma risk and patient prognosis

Transforming growth factor beta (TGF-β) plays an important role in carcinogenesis. Two polymorphisms in the TGF-β1 gene (-509C/T and 869T/C) were described to influence susceptibility to gastric and breast cancers. The 869T/C polymorphism was also associated with overall survival in breast cancer pa...

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Veröffentlicht in:	Tumor biology 2015-08, Vol.36 (8), p.6525-6532
Hauptverfasser:	Vieira de Castro, Joana, Gonçalves, Céline S., Costa, Sandra, Linhares, Paulo, Vaz, Rui, Nabiço, Ricardo, Amorim, Júlia, Viana-Pereira, Marta, Reis, Rui M., Costa, Bruno M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers, Tumor - genetics Biomedical and Life Sciences Biomedicine Cancer Research Case-Control Studies Female Genetic Association Studies Genetic Predisposition to Disease Genotype Glioblastoma - genetics Glioblastoma - pathology Glioma - epidemiology Glioma - genetics Glioma - pathology Humans Kaplan-Meier Estimate Male Middle Aged Polymorphism, Single Nucleotide Prognosis Research Article Risk Factors Transforming Growth Factor beta1 - genetics
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